MRI-guided Bone Marrow Biopsies of Prostate Cancer Patients

MRI-guided Bone Marrow Biopsies of Advanced CaP Patients

The purpose of this study is to target lesions of the prostate in the bone and to biopsy these lesions using MRI to identify the areas.

• This study involves a one-time, MRI-guided bone marrow biopsy. Prior to this procedure, patients will need to have a bone scan performed within the last three months and a PSA blood test drawn within one month of registration to the study.
• Patients are also required to participate in the DFCI research study "Collection of Specimens and Clinical Data for Patients with Prostate Cancer or at High Risk for Prostate Cancer".

Inclusion Criteria:

• Histologic diagnosis of prostate cancer
• Bone scan consistent with or suspicious of metastatic prostate cancer within last three months
• Platelet count > 50,000/ul
• PT and aPTT < 1.5 x control
• At least one week removed from taking aspirin or coumadin
• Currently participating in protocol "Collection of Specimens and Clinical Data for Patients with Prostate Cancer or at High Risk for Prostate Cancer"

Exclusion Criteria:

• Devices incompatible to MR studies (e.g. pacemakers, ear implants, etc.)