Effect of KW-3902IV in Combination With IV Furosemide on Renal Function in Subjects With CHF and Renal Impairment

Effect of KW-3902IV in Combination With IV Furosemide on Renal Function in Subjects With Congestive Heart Failure (CHF) and Renal Impairment

The purpose of this study is to characterize the safety and tolerability of KW-3902IV and measure its effect on renal function.

Inclusion Criteria:

• Stable congestive heart failure
• Impaired renal function
• Taking oral loop diuretic

Exclusion Criteria:

• Acutely decompensated (unstable) and end stage heart failure
• Diuretics other than loop diuretics
• Pregnant or nursing
• Inability to follow instructions
• Participation in another clinical trial within past 30 days