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The primary aim of the study is to increase the success rate of cecal intubation in first colonoscopy and in repeated colonoscopy for the first failed procedure. The secondary aims are to assess the procedure time, the terminal ileum intubation rate, the endoscopist satisfaction score, the patients' acceptance, the complication rate of these two procedures, and the intravenous sedative drugs used.
Currently there is no consensus in how to improve the success rate of colonoscopy procedure given the fact that 10% of the procedures may fail. It has been suggested that using variable stiffness colonoscope (a colonoscope with a shaft that the stiffness can be altered), or even more sophisticated magnetic imaging colonoscopy (colonoscopy performed under a magnetic position detection sensor), could improve the success rate. However, these kinds of equipment are either expensive or not always available in the daily clinical practice. From some recent studies it was shown that adding a transparent cap to the tip of the colonoscope may improve the procedure success rate without increasing the complication rate of the procedure. The cost of the cap is cheap and it is available in almost every endoscopy center. Therefore the cap-assisted colonoscopy method may be an alternative which may improve the success rate of colonoscopy procedure, and reduce the pain and discomfort related to the procedure.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1 | Active Comparator | Cap-assisted Colonoscopy |
|
| 2 | Placebo Comparator | Regular Colonoscopy |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cap-assisted colonoscopy | Procedure | Cap-assisted colonoscopy |
| |
| Cap-assisted colonoscopy |
| Measure | Description | Time Frame |
|---|---|---|
| The success rate of cecal intubation | 24 hours |
| Measure | Description | Time Frame |
|---|---|---|
| The procedure time to achieve cecal intubation | 24 hours | |
| Success rate in achieving terminal ileum intubation | 24 hours | |
| The procedure time to achieve terminal ileum intubation |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Y T Lee, MD | Department of Medicine & Therapeutics, Prince of Wales Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Endoscopy Center, Alice Ho Miu Ling Nethersole Hospital | Hong Kong | China | ||||
| Endoscopy Center, Prince of Wales Hospital |
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| Procedure |
Cap-assisted colonoscopy |
|
| 24 hours |
| Complications related to the procedure | 24 hours |
| The procedure difficulty as assessed by the endoscopist using a 10 cm visual analog scale | 24 hours |
| The procedure difficulty of polypectomy if indicated as assessed by the endoscopist using a 10 cm visual analog scale | 24 hours |
| The patient's pain score as assessed by the patient using a visual analog scale right after he regains full consciousness, which is assessed by accurately performing a deduction test (100 minus 7 test, correct for three deductions), before discharge | 24 hours |
| The dose of the intravenous drugs used | 24 hours |
| Hong Kong |
| China |