Efficacy and Safety of SPD465 in Adults With ADHD

A Phase III, Randomized, Double-blind, Multi-center, Placebo-Controlled, Parallel-Group, Safety and Efficacy Study of SPD465 in Adults With Attention-Deficit Hyperactivity Disorder (ADHD).

The purpose of this study is to assess the safety and effectiveness of SPD465 compared to placebo (a capsule with no medication in it) in the treatment of ADHD. The study will also look at how SPD465 affects sleep and how the participants perceive their quality of life.

Inclusion Criteria:

• Primary diagnosis of ADHD
• Baseline ADHD-RS-IV score >= 24
• Non-pregnant females of childbearing potential must comply with contraceptive restrictions

Exclusion Criteria:

• Significantly underweight or morbidly obese
• Comorbid psychiatric diagnosis with significant symptoms such as Axis II disorders or severe Axis I disorders
• History of seizure, tic disorder, or a current diagnosis and/or family history of Tourette's Disorder