Comparison of Three Different Strategies to Prevent Propofol Induced Pain During Infusion

Comparison of Three Different Strategies to Prevent Propofol Induced Pain During Infusion

Propofol is a popular intravenous drug to induce anesthesia but it causes local pain with an incidence between 40 and 90%. Three different strategies to prevent propofol induced pain will be studied compared with placebo. Pain will be scored with a four-point scale.

Inclusion Criteria:

Healthy adults (ASA 1-2) for scheduled surgery under general anesthesia with propofol

Exclusion Criteria:

• pregnant
• sedative or analgesic drug 24h before surgery
• allergy with drug used in the study
• difficulty of communication
• absence of informed written consent