Natural History Study of Azathioprine Adherence

Measurement of Compliance in Renal Transplant Recipients

This study began in 1993 as a prospective, natural history study of renal transplant patients' medication compliance measured by using an electronic monitor on the cap of medication vials. Hypothesis: Poor medication compliance predicts adverse outcomes. Enrollment is closed.

• The study is complete. Patient recruitment is closed and active patient involvement in the study has ended.
• Statistical analysis of monitor records and new patient outcome data continues

Inclusion Criteria:

• Kidney transplant recipient
• Discharged from hospital with functioning graft,not on dialysis
• Prescribed azathioprine

Exclusion Criteria:

• Unable to give informed consent
• Non English speaking
• Previous or concurrent organ transplant other than kidney
• Taking liquid form of azathioprine
• Followed outside of the United states