A Study To Investigate The Effect Of PD-217,014 On Abdominal Pain/Discomfort In Patients With IBS.

A Multi-Center, Double-Blind, Randomized, Placebo-Controlled, Parallel Group Study To Investigate The Effect Of Pd-217,014 In Patients With Irritable Bowel Syndrome (IBS)

The purpose of this study is to determine the effectiveness of PD-217,014 in the treatment of abdominal pain/discomfort associated with irritable bowel disease.

Inclusion Criteria:

• Males and females having Irritable bowel syndrome as defined by the Rome II criteria.
• Patients must have had normal examination of colon anatomy within the last 5 years

Exclusion Criteria:

• Patient with an organic gastrointestinal disease.
• Patients with poor renal function.
• Patients with severe constipation.