Parecoxib In Post Surgery (Hemicolectomy) Pain

A Multicenter, Open Label, Pilot Study To Evaluate Analgesic Activity And Safety Of Parecoxib 40 Mg IV In Patients Undergoing Hemicolectomy, In The Optimal Management Of Acute Post-Operative Pain Of Surgical Patients

This is a phase III, multicenter, open label, pilot to evaluate the analgesic efficacy and safety of parecoxib 40 mg IV in the treatment of the pain following hemicolectomy in an optimal management of the surgical patient

The study was terminated prematurely due to recruitment issues on 31 January 2006. Safety concerns did not lead to the decision to terminate this study.

Inclusion Criteria:

• patients hospitalised for resection of left/right colon;
• preoperative health graded as ASA <3.

Exclusion Criteria:

• patients with any type of metastatic cancer, particularly metastatic colon cancer;
• patients with familial adenomatous polyps (sporadic adenomatous polyps are accepted);