Instillation of artificial tears is standard treatment in dry eye syndrome and in patients experiencing dry eye symptoms when wearing contact lenses. Povidone K25 eye drops (povidone) is an isotonic solution containing povidone to simulate normal tears viscosity. Safety and local tolerability of Povidone K25 is evaluated in healthy volunteers in comparison to placebo eye drops.

Inclusion Criteria:

• Healthy subjects
• Older than 18 years
• Ocular discomfort less than 20 mm on 100 mm visual analogue scale (VAS) prior to treatment

Exclusion Criteria:

• Known hypersensitivity to any of the constituents of the medications
• Known allergic disposition (e.g. hay fever)
• Wearing of contact lenses
• Any kind of current eye disease (e.g. dry eye)

Additional exclusion criteria are defined in the protocol