The purposes of this study are to determine:

• The safety of the study medication and any side effects that might be associated with it
• Whether the study medication can help patients with high levels of "bad" cholesterol (low-density lipoprotein-cholesterol [LDL-C]), alone or in combination with additional study medication

Inclusion Criteria:

• Men and women between 18 and 80 years of age
• People with abnormal cholesterol levels

Exclusion Criteria:

• People with diabetes
• People whose blood pressure >160/95 mm Hg, on or off blood pressure medicine
• People who have had frequent chest pain or unstable angina, a heart attack or a heart procedure including stent placement, within the past 3 months