A Study of the Safety and Efficacy of Synvisc in Patients With Symptomatic Ankle Osteoarthritis

This clinical study is to evaluate the safety and efficacy of Synvisc in patients with symptomatic ankle osteoarthritis (OA). Patients will be given Synvisc, with the possible administration of a second injection where insufficient symptomatic pain relief was experienced during the initial 3 months follow up period.

Inclusion Criteria:

• Patients with symptomatic OA pain of ankle (talo-crural)

Exclusion Criteria:

• Patients with current or prior conditions or treatments that would impede measurements of efficacy or safety