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| ID | Type | Description | Link |
|---|---|---|---|
| MK0476-327 | |||
| 2005_038 |
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The purpose of this trial is to evaluate the efficacy and safety of an investigational drug in adult patients with allergic rhinitis.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1 | Experimental | montelukast sodium 5 mg, QD 2-weeks |
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| 2 | Experimental | montelukast sodium 10 mg QD 2-weeks |
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| 3 | Active Comparator | Pranlukast 225 mg BID 2-weeks |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| montelukast sodium | Drug | montelukast sodium; 5 mg, 10 mg QD 2-weeks. |
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| Measure | Description | Time Frame |
|---|---|---|
| Composite Nasal Symptom Score |
| Measure | Description | Time Frame |
|---|---|---|
| Daytime nasal symptom score, Nighttime nasal symptom score |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Medical Monitor | Merck Sharp & Dohme LLC | Study Director |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 18946234 | Result | Okubo K, Baba K. A double-blind non-inferiority clinical study of montelukast, a cysteinyl leukotriene receptor 1 antagonist, compared with pranlukast in patients with seasonal allergic rhinitis. Allergol Int. 2008 Dec;57(4):383-90. doi: 10.2332/allergolint.O-08-533. Epub 2008 Nov 1. |
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| ID | Term |
|---|---|
| D006255 | Rhinitis, Allergic, Seasonal |
| ID | Term |
|---|---|
| D065631 | Rhinitis, Allergic |
| D012220 | Rhinitis |
| D009668 | Nose Diseases |
| D012140 | Respiratory Tract Diseases |
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| ID | Term |
|---|---|
| C093875 | montelukast |
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| Comparator: pranlukast | Drug | Pranlukast 225 mg BID 2-weeks. |
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| D012130 |
| Respiratory Hypersensitivity |
| D010038 | Otorhinolaryngologic Diseases |
| D006969 | Hypersensitivity, Immediate |
| D006967 | Hypersensitivity |
| D007154 | Immune System Diseases |