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| ID | Type | Description | Link |
|---|---|---|---|
| TRF470116 | Other Grant/Funding Number | Thailand Research Fund |
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| Name | Class |
|---|---|
| Thailand Research Fund | OTHER |
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The objective of the study is to evaluate the results of using air versus expansile gas (perfluoropropane) in the treatment of rhegmatogenous retinal detachment by pneumatic retinopexy, comparing the retinal reattachment rate and post-operative visual recovery.
To the best of the investigators' knowledge there have been no clinical trials to compare air and expansile gas in pneumatic retinopexy. The investigators hypothesize that both air and expansile gas have the same properties of gas and remain in the eye for 5-6 days which is long enough to have moderate chorioretinal adhesion to seal the retinal break. If the investigators can prove that air is equivalent to expansile gas in this procedure, it can save a lot of money for the country. Therefore, the investigators are conducting a randomised controlled double-blind study to compare the results of using air and perfluoropropane in pneumatic retinopexy for treatment of rhegmatogenous retinal detachment.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 2 | Active Comparator | air vs perfluoropropane gas in pneumatic retinopexy |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| air | Procedure | 0.3 ml of filtered air |
| |
| expansile gas |
| Measure | Description | Time Frame |
|---|---|---|
| The retinal reattachment rate (calculated from the number of patients who had post-operative attached retinas divided by the total number of patients treated) | 1 week |
| Measure | Description | Time Frame |
|---|---|---|
| The final visual recovery (calculated from the difference between pre-operative and post-operative visual acuity) | 6 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Yosanan Yospaiboon, M.D. | Khon Kaen University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Eye outpatients department, Srinagarind Hospital, Khon Kaen University | Khon Kaen | Changwat Khon Kaen | 40002 | Thailand |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 20937993 | Result | Sinawat S, Ratanapakorn T, Sanguansak T, Prompol S, Laopaiboon M, Yospaiboon Y. Air vs perfluoropropane gas in pneumatic retinopexy: a randomized noninferiority trial. Arch Ophthalmol. 2010 Oct;128(10):1243-7. doi: 10.1001/archophthalmol.2010.230. | |
| 32408387 | Derived | Schwartz SG, Flynn HW Jr, Wang X, Kuriyan AE, Abariga SA, Lee WH. Tamponade in surgery for retinal detachment associated with proliferative vitreoretinopathy. Cochrane Database Syst Rev. 2020 May 13;5(5):CD006126. doi: 10.1002/14651858.CD006126.pub4. |
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| ID | Term |
|---|---|
| D012163 | Retinal Detachment |
| ID | Term |
|---|---|
| D012164 | Retinal Diseases |
| D005128 | Eye Diseases |
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| ID | Term |
|---|---|
| D000388 | Air |
| ID | Term |
|---|---|
| D001272 | Atmosphere |
| D004777 | Environment |
| D055669 | Ecological and Environmental Phenomena |
| D001686 | Biological Phenomena |
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| Procedure |
0.3 ml of perfluoropropane gas |
|
| D008685 |
| Meteorological Concepts |
| D004778 | Environment and Public Health |