Changes in Cardiovascular Hemodynamics During Peritoneal Dialysis

Changes in Cardiovascular Hemodynamics During Peritoneal Dialysis; the Effect of Different Dialysates

During peritoneal dialysis, water is removed from the body. This sometimes occurs at rates of up to 500 ml/h. During shifts with dialysate with high glucose content, an increase in blood pressure has been described. The effect upon central hemodynamics is unknown. The researchers are investigating the effects of low and high glucose dialysate and icodextrin on cardiac output, stroke volume, pulse rate and blood pressure. The researchers have hypothesized that the effects seen are induced by vasopressin.

Inclusion Criteria:

• Peritoneal dialysis patients

Exclusion Criteria:

• Insulin dependent diabetes mellitus
• AV-fistula, cardial arrhythmia persistence, or severe cardiac and lung disease
• Recent infectious disease
• Severe psychiatric disease
• Hypersensitivity to icodextrin