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| Name | Class |
|---|---|
| Medtronic | INDUSTRY |
The purpose of this study is to determine long-term efficacy of continuous IPu liatermin infusion administered with concomitant standard anti-Parkinsonian therapy.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Liatermin | Experimental | Bilateral continuous infusion of liatermin for up to 24 months. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Liatermin | Biological | Liatermin |
|
| Measure | Description | Time Frame |
|---|---|---|
| Percent change in UPDRS | 24 months |
| Measure | Description | Time Frame |
|---|---|---|
| Incidence of treatment emergent and device related adverse events | 24 months |
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Inclusion Criteria: - Completion of the 20020168 protocol
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| Name | Affiliation | Role |
|---|---|---|
| MD | Amgen | Study Director |
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| Label | URL |
|---|---|
| AmgenTrials clinical trials website | View source |
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| ID | Term |
|---|---|
| D010300 | Parkinson Disease |
| ID | Term |
|---|---|
| D020734 | Parkinsonian Disorders |
| D001480 | Basal Ganglia Diseases |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D009069 | Movement Disorders |
| D000080874 | Synucleinopathies |
| D019636 | Neurodegenerative Diseases |
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| ID | Term |
|---|---|
| D051100 | Glial Cell Line-Derived Neurotrophic Factor |
| ID | Term |
|---|---|
| D051098 | Glial Cell Line-Derived Neurotrophic Factors |
| D009414 | Nerve Growth Factors |
| D036341 | Intercellular Signaling Peptides and Proteins |
| D010455 | Peptides |
| D000602 | Amino Acids, Peptides, and Proteins |
| D011506 | Proteins |
| D009419 | Nerve Tissue Proteins |
| D001685 | Biological Factors |
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