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| ID | Type | Description | Link |
|---|---|---|---|
| R01AT002454 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Center for Complementary and Integrative Health (NCCIH) | NIH |
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The purpose of this study is to determine the effects of a tai chi exercise program on functional capacity and health-related quality of life in patients with chronic heart failure (HF). This study will also examine the way tai chi influences mental, physical, and social functioning.
HF is a major public health problem in the United States, affecting approximately 5 million adults. Despite recent advances in pharmacologic therapy and technologic devices, HF is the most common reason for hospitalization among Medicare patients and is reaching epidemic proportions as the population ages. New and inexpensive interventions that can improve functional capacity and quality of life and can delay disease progression are needed. Tai chi is a popular mind-body exercise that is a potential treatment for heart disease. This exercise incorporates both gentle physical activity and meditation, and it may be particularly suited to frail patients with HF. This study will examine the effects of a tailored tai chi program on functional capacity and quality of life in patients with HF.
Participants will be randomly assigned to either a tai chi program or heart health education for 12 weeks. Participants in both groups will undergo a bicycle stress test at study entry and will receive weekly training sessions of their assigned intervention. Self-report scales and questionnaires will be used to assess participants at study start and at the end of 12 weeks.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Tai Chi | Experimental | 12-week tai chi program |
|
| Heart Health Education | Active Comparator | 12-week attention control |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| 12-week Tai Chi Program | Behavioral | 24 tai chi sessions. 2 sessions/week for 12 weeks. |
| |
| Measure | Description | Time Frame |
|---|---|---|
| HF-specific quality of life | baseline, midpoint, endpoint, 6mo | |
| functional capacity | baseline and endpoint | |
| Walking Test | baseline, midpoint, endpoint |
| Measure | Description | Time Frame |
|---|---|---|
| General quality of life | baseline, midpoint, endpoint, 6mo | |
| mood and emotional status | baseline, midpoint, endpoint, 6mo | |
| exercise self-efficacy |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Russell S. Phillips, MD | Beth Israel Deaconess Medical Center, Harvard Medical School | Principal Investigator |
| Ellen P. McCarthy, PhD | Beth Israel Deaconess Medical Center, Harvard Medical School | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | United States | ||
| Beth Israel Deaconess Medical Center, Harvard Medical School |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 15465501 | Background | Yeh GY, Wood MJ, Lorell BH, Stevenson LW, Eisenberg DM, Wayne PM, Goldberger AL, Davis RB, Phillips RS. Effects of tai chi mind-body movement therapy on functional status and exercise capacity in patients with chronic heart failure: a randomized controlled trial. Am J Med. 2004 Oct 15;117(8):541-8. doi: 10.1016/j.amjmed.2004.04.016. | |
| 21518942 | Result | Yeh GY, McCarthy EP, Wayne PM, Stevenson LW, Wood MJ, Forman D, Davis RB, Phillips RS. Tai chi exercise in patients with chronic heart failure: a randomized clinical trial. Arch Intern Med. 2011 Apr 25;171(8):750-7. doi: 10.1001/archinternmed.2011.150. |
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| ID | Term |
|---|---|
| D006333 | Heart Failure |
| ID | Term |
|---|---|
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
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| 12-week Education Program |
| Behavioral |
24 Educational sessions. 2 sessions/week for 12 weeks. |
|
| baseline, midpoint, endpoint, 6mo |
| sense of coherence | baseline, midpoint, endpoint, 6mo |
| utility assessment | baseline, midpoint, endpoint, 6mo |
| beliefs, attitudes, and expectations | baseline, midpoint, endpoint |
| physical activity level | baseline, midpoint, endpoint |
| perceived social support | baseline, midpoint, endpoint |
| neurohormonal status | baseline, midpoint, endpoint |
| autonomic tone, heart rate variability | baseline and endpoint |
| echocardiography | baseline and endpoint |
| costs and use of HF services | baseline and endpoint |
| Boston |
| Massachusetts |
| 02215 |
| United States |
| Brigham and Women's Hospital | Boston | Massachusetts | 02215 | United States |
| Lown Cardiovascular Center | Brookline | Massachusetts | 02446 | United States |