Tight Glycemic Control in Critical Care Patients

Tight Glycemic Control in Patients Hospitalized in a Medical-Surgery Intensive Care Unit: A Randomized Study

The purpose of this study is to evaluate the impact of tight control of serum glucose levels with an intensive insulin treatment in patients hospitalized in an intensive care unit with medical and surgical patients.

Reduction of morbidity-mortality in critical care patients with tight glycemic control had been proven in surgical patients only.

Study Hypothesis: In critical care patients, medical or surgical, a glucose serum level between 80 - 110 mg/dL means a lower mortality than patients with glucose levels of more than 110 mg/dL.

Inclusion Criteria:

• 15 years of age or older,
• Probability of staying in critical care for more than 48 hours,
• Agreement with the informed consent.

Exclusion Criteria:

• Pregnancy,
• Participating in other trials,
• Diabetic keto-acidosis or diabetic hyperosmolar state,
• Moribund
• Do-not-resuscitate orders,
• Reentry to the critical care unit of the same patient.