Interactions Between Cocaine and Ethanol and Disulfiram - 1

Interactions Between IV Cocaine and Ethanol and Oral Disulfiram

The purpose of this study is to assess potential interactions between intravenous cocaine and ethanol and oral disulfiram.

This is a two-site, double blind, placebo-controlled inpatient study to determine the cardiovascular and psychiatric safety of alcohol use in cocaine-dependent subjects who had used cocaine after treatment with disulfiram.

Inclusion Criteria:

• Must meet DSM-4 criteria for cocaine abuse or dependence and are not seeking treatment.
• Ability to verbalize understanding of consent form and provide written informed consent and verbalize willingness to complete study procedures; be able to comply with protocol requirements.

Exclusion Criteria:

• Please contact site for more information.