A Study To Assess The Safety And Efficacy Of SU11248 In P... | NCT00075218

Label	Type	Description	Intervention Names
B	Placebo Comparator		Drug: Placebo
A	Active Comparator		Drug: SU011248

Name	Type	Description	Arm Group Labels	Other Names
Placebo	Drug	50 mg taken orally once a day. 6 week treatment cycle (Schedule 4/2) 4 weeks on study drug/2 weeks off study drug.	B

Measure	Description	Time Frame
Time to Tumor Progression (TTP) as Assessed by Imaging Studies at End of Double-blind Treatment Phase	Time from randomization to first documentation of objective tumor progression based on the assessment of an independent, third-party imaging laboratory using RECIST (Response Evaluation Criteria in Solid Tumors).	Day 28 of each 6-week cycle : duration of double-blind treatment phase
Time to Tumor Progression (TTP) as Assessed in the Double-blind Treatment Phase at End of Study	Time from randomization to first documentation of objective tumor progression based on the assessment of an independent, third-party imaging laboratory using RECIST (Response Evaluation Criteria in Solid Tumors).	Day 28 of each 6-week cycle : duration of double-blind treatment phase after Last Subject Last Visit (LSLV)

Measure	Description	Time Frame
Progression Free Survival (PFS)	Time from randomization to first documentation of objective tumor progression or to death due to any cause (on treatment or within 28 days of last dose).	Day 28 of each cycle : duration of double-blind treatment phase
Overall Survival Status of Subjects

Name	Affiliation	Role
Pfizer CT.gov Call Center	Pfizer	Study Director

Facility	Status	City	State	ZIP	Country	Contacts
Pfizer Investigational Site		Duarte	California	91010	United States
Pfizer Investigational Site

PubMed Identifier	Type	Citation	Retractions
17046465	Derived	Demetri GD, van Oosterom AT, Garrett CR, Blackstein ME, Shah MH, Verweij J, McArthur G, Judson IR, Heinrich MC, Morgan JA, Desai J, Fletcher CD, George S, Bello CL, Huang X, Baum CM, Casali PG. Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial. Lancet. 2006 Oct 14;368(9544):1329-38. doi: 10.1016/S0140-6736(06)69446-4.

Label	URL
To obtain contact information for a study center near you, click here.	View source

ID	Title	Description
FG000	Sunitinib Double-Blind Treatment	Starting dose: 50 mg orally once daily as a single agent for 4 consecutive weeks followed by a 2-week off-treatment period to form a complete cycle of 6 weeks. (Schedule 4/2). Subjects received best supportive care in addition to the study treatment.
FG001

Serious Adverse Events

Term	Organ System	Source Vocabulary	Assessment Type	Statistical Information
Anaemia	Blood and lymphatic system disorders	MedDRA (11.1)	Systematic Assessment	EG00011 affected228 at risk EG0011 affected114 at risk EG00210 affected255 at risk
Thrombocytopenia	Blood and lymphatic system disorders		Systematic Assessment	EG0005 affected228 at risk EG0010 affected114 at risk EG0024 affected255 at risk
Neutropenia	Blood and lymphatic system disorders		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Febrile neutropenia	Blood and lymphatic system disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Leukopenia	Blood and lymphatic system disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Cardiac arrest	Cardiac disorders		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Cardiac disorder	Cardiac disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Cardiac failure	Cardiac disorders		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Cardiomyopathy	Cardiac disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Ejection fraction decreased	Cardiac disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Left ventricular failure	Cardiac disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Mitral valve imcompetence	Cardiac disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Pyloric stenosis	Congenital, familial and genetic disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Hypothyroidism	Endocrine disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0024 affected255 at risk
Abdominal pain	Gastrointestinal disorders		Systematic Assessment	EG00013 affected228 at risk EG0016 affected114 at risk EG00229 affected255 at risk
Nausea	Gastrointestinal disorders		Systematic Assessment	EG0005 affected228 at risk EG0013 affected114 at risk EG0028 affected255 at risk
Vomiting	Gastrointestinal disorders		Systematic Assessment	EG0005 affected228 at risk EG0014 affected114 at risk EG00212 affected255 at risk
Ascites	Gastrointestinal disorders		Systematic Assessment	EG0004 affected228 at risk EG0011 affected114 at risk EG0023 affected255 at risk
Diarrhoea	Gastrointestinal disorders		Systematic Assessment	EG0004 affected228 at risk EG0010 affected114 at risk EG0024 affected255 at risk
Abdominal distension	Gastrointestinal disorders		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Constipation	Gastrointestinal disorders		Systematic Assessment	EG0002 affected228 at risk EG0011 affected114 at risk EG0025 affected255 at risk
Gastrointestinal haemorrhage	Gastrointestinal disorders		Systematic Assessment	EG0002 affected228 at risk EG0013 affected114 at risk EG0024 affected255 at risk
Intestinal obstruction	Gastrointestinal disorders		Systematic Assessment	EG0002 affected228 at risk EG0011 affected114 at risk EG0022 affected255 at risk
Melaena	Gastrointestinal disorders		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Abdominal pain upper	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Anal fistula	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Gastric haemorrhage	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Gastric ulcer	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Gastritis	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Gastritis haemorrhagic	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Gastrointestinal obstruction	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Haematemesis	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0023 affected255 at risk
Haemorrhoids	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Intestinal haemorrhage	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Oesophageal haemorrhage	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Rectal haemorrhage	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0025 affected255 at risk
Small intestinal obstruction	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Ileus	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0012 affected114 at risk EG0022 affected255 at risk
Subileus	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Disease progression	General disorders		Systematic Assessment	EG0008 affected228 at risk EG0014 affected114 at risk EG00233 affected255 at risk
Pyrexia	General disorders		Systematic Assessment	EG0008 affected228 at risk EG0011 affected114 at risk EG00211 affected255 at risk
Fatigue	General disorders		Systematic Assessment	EG0002 affected228 at risk EG0011 affected114 at risk EG0023 affected255 at risk
Oedema peripheral	General disorders		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Asthenia	General disorders		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0023 affected255 at risk
Chills	General disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Drug interaction	General disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
General physical health deterioration	General disorders		Systematic Assessment	EG0001 affected228 at risk EG0013 affected114 at risk EG0024 affected255 at risk
Multi-organ failure	General disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Oedema	General disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Chest pain	General disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0023 affected255 at risk
Acute hepatic failure	Hepatobiliary disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Bile duct stone	Hepatobiliary disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Cholecystitis acute	Hepatobiliary disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Cholelithiasis	Hepatobiliary disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Cholestasis	Hepatobiliary disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Hepatic failure	Hepatobiliary disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Hepatic function abnormal	Hepatobiliary disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Hepatic haemorrhage	Hepatobiliary disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Catheter sepsis	Infections and infestations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Central line infection	Infections and infestations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Infection	Infections and infestations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Mediastinitis	Infections and infestations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Pneumonia	Infections and infestations		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0024 affected255 at risk
Staphylococcal sepsis	Infections and infestations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Urinary tract infection	Infections and infestations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Viral infection	Infections and infestations		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Bacteraemia	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0022 affected255 at risk
Cystitis	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Lower respiratory tract infection	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Wound dehiscence	Injury, poisoning and procedural complications		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Aspartate aminotransferase increased	Investigations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Blood creatinine increased	Investigations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Haemoglobin decreased	Investigations		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0022 affected255 at risk
Dehydration	Metabolism and nutrition disorders		Systematic Assessment	EG0004 affected228 at risk EG0010 affected114 at risk EG00210 affected255 at risk
Hypoglycaemia	Metabolism and nutrition disorders		Systematic Assessment	EG0004 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Food intolerance	Metabolism and nutrition disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Hypercalcaemia	Metabolism and nutrition disorders		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Hypocalcaemia	Metabolism and nutrition disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Hypokalaemia	Metabolism and nutrition disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Anorexia	Metabolism and nutrition disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0023 affected255 at risk
Appetite disorder	Metabolism and nutrition disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Back pain	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0001 affected228 at risk EG0012 affected114 at risk EG0021 affected255 at risk
Fistula	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Flank pain	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Muscle spasms	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Pain in extremity	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Bone pain	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Intervertebral disc protrusion	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Mobility decreased	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Tumour haemorrhage	Neoplasms benign, malignant and unspecified (incl cysts and polyps)		Systematic Assessment	EG0003 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Haemorrhagic tumour necrosis	Neoplasms benign, malignant and unspecified (incl cysts and polyps)		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Multiple myeloma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Tumour associated fever	Neoplasms benign, malignant and unspecified (incl cysts and polyps)		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Tumour lysis syndrome	Neoplasms benign, malignant and unspecified (incl cysts and polyps)		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Cancer pain	Neoplasms benign, malignant and unspecified (incl cysts and polyps)		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Cerebral ischaemia	Nervous system disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Encephalopathy	Nervous system disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Myoclonus	Nervous system disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Somnolence	Nervous system disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Syncope	Nervous system disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Transient ischaemic attack	Nervous system disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Cerebrovascular accident	Nervous system disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Paralysis	Nervous system disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Insomnia	Psychiatric disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Nervousness	Psychiatric disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Haematuria	Renal and urinary disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Nephrotic syndrome	Renal and urinary disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Oliguria	Renal and urinary disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Renal colic	Renal and urinary disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Renal failure acute	Renal and urinary disorders		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Urinary retention	Renal and urinary disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Hydronephrosis	Renal and urinary disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Pelvic pain	Reproductive system and breast disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Pulmonary embolism	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0004 affected228 at risk EG0011 affected114 at risk EG0022 affected255 at risk
Pneumothorax	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Pulmonary hypertension	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Rash	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Deep vein thrombosis	Vascular disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Haemorrhage	Vascular disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Hypertensive crisis	Vascular disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Thrombosis	Vascular disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Circulatory collapse	Vascular disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Haemolytic anaemia	Blood and lymphatic system disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Lymphopenia	Blood and lymphatic system disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Cardio-respiratory arrest	Cardiac disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Angina pectoris	Cardiac disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Bradycardia	Cardiac disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Cardiac failure congestive	Cardiac disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Myocardial infarction	Cardiac disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Pericardial effusion	Cardiac disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Ventricular hypokinesia	Cardiac disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Epidermolysis	Congenital, familial and genetic disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Abdominal discomfort	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Anal haemorrhage	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Duodenal fistula	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Duodenal ulcer	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Dyspepsia	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Enterocutaneous fistula	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Gastrooesophageal reflux disease	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Inguinal hernia	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Intra-abdominal haemorrhage	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Large intestinal haemorrhage	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Peritoneal haemorrhage	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Tongue haemorrhage	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Upper gastrointestinal haemorrhage	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Performance status decreased	General disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Catheter related complication	General disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Impaired healing	General disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Infusion site extravasation	General disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Mucosal inflammation	General disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Pain	General disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Pneumatosis	General disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Ulcer haemorrhage	General disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Cholecystitis	Hepatobiliary disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Hepatotoxicity	Hepatobiliary disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Gastroenteritis	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Abdominal abscess	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Bacterial infection	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Campylobacter infection	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Cellulitis	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Empyema	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Gastrointestinal infection	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Liver abscess	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Perirectal abscess	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Respiratory tract infection	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Sepsis	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Urosepsis	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Device malfunction	Injury, poisoning and procedural complications		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Feeding tube complication	Injury, poisoning and procedural complications		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Medication error	Injury, poisoning and procedural complications		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Neck injury	Injury, poisoning and procedural complications		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Skin laceration	Injury, poisoning and procedural complications		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Ammonia increased	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Blood bilirubin increased	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Blood creatine phosphokinase increased	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Blood potassium decreased	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Blood pressure increased	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Weight decreased	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Cachexia	Metabolism and nutrition disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Hypochloraemia	Metabolism and nutrition disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Hyponatraemia	Metabolism and nutrition disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Musculoskeletal pain	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Myalgia	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Neck pain	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Rotator cuff syndrome	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Hepatic neoplasm malignant	Neoplasms benign, malignant and unspecified (incl cysts and polyps)		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Metastases to liver	Neoplasms benign, malignant and unspecified (incl cysts and polyps)		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Neurilemmoma benign	Neoplasms benign, malignant and unspecified (incl cysts and polyps)		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Tumour perforation	Neoplasms benign, malignant and unspecified (incl cysts and polyps)		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Hepatic encephalopathy	Nervous system disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Lethargy	Nervous system disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Cerebral haemorrhage	Nervous system disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Coma	Nervous system disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Convulsion	Nervous system disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Dizziness	Nervous system disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Guillain-Barre syndrome	Nervous system disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Intracranial venous sinus thrombosis	Nervous system disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Lacunar infarction	Nervous system disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Loss of consciousness	Nervous system disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Paraesthesia	Nervous system disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Confusional state	Psychiatric disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0024 affected255 at risk
Agitation	Psychiatric disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Completed suicide	Psychiatric disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Renal failure	Renal and urinary disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Renal impairment	Renal and urinary disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Dysuria	Renal and urinary disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Uterine polyp	Reproductive system and breast disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Vaginal haemorrhage	Reproductive system and breast disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Epistaxis	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Dyspnoea	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Pleural effusion	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Lung consolidation	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Diabetic ulcer	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Palmar-plantar erythrodysaesthesia syndrome	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Hepatic embolisation	Surgical and medical procedures		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Stent placement	Surgical and medical procedures		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Hypertension	Vascular disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0024 affected255 at risk
Hypotension	Vascular disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Thrombophlebitis	Vascular disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Embolism	Vascular disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Jugular vein thrombosis	Vascular disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk

Other Adverse Events

Term	Organ System	Source Vocabulary	Assessment Type	Statistical Information
Anaemia	Blood and lymphatic system disorders	MedDRA (11.1)	Systematic Assessment	EG00046 affected228 at risk EG00110 affected114 at risk EG00280 affected255 at risk
Neutropenia	Blood and lymphatic system disorders		Systematic Assessment	EG00033 affected228 at risk EG0011 affected114 at risk EG00264 affected255 at risk
Thrombocytopenia	Blood and lymphatic system disorders		Systematic Assessment	EG00033 affected228 at risk EG0011 affected114 at risk EG00244 affected255 at risk
Leukopenia	Blood and lymphatic system disorders		Systematic Assessment	EG00011 affected228 at risk EG0011 affected114 at risk EG00222 affected255 at risk
Lymphopenia	Blood and lymphatic system disorders		Systematic Assessment	EG0002 affected228 at risk EG0011 affected114 at risk EG0029 affected255 at risk
Febrile neutropenia	Blood and lymphatic system disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Hand and foot syndrome secondary to sickle cell anaemia	Blood and lymphatic system disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Lymphadenopathy	Blood and lymphatic system disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Pancytopenia	Blood and lymphatic system disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Ejection fraction decreased	Cardiac disorders		Systematic Assessment	EG00019 affected228 at risk EG0013 affected114 at risk EG0025 affected255 at risk
Left ventricular dysfunction	Cardiac disorders		Systematic Assessment	EG0004 affected228 at risk EG0011 affected114 at risk EG0026 affected255 at risk
Tachycardia	Cardiac disorders		Systematic Assessment	EG0003 affected228 at risk EG0010 affected114 at risk EG0024 affected255 at risk
Bradycardia	Cardiac disorders		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Cardiac disorder	Cardiac disorders		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Cardiomyopathy	Cardiac disorders		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Palpitations	Cardiac disorders		Systematic Assessment	EG0002 affected228 at risk EG0012 affected114 at risk EG0022 affected255 at risk
Angina pectoris	Cardiac disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Arrhythmia supraventricular	Cardiac disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Atrial fibrillation	Cardiac disorders		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Cardiac arrest	Cardiac disorders		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Cardiac failure	Cardiac disorders		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Cardiomegaly	Cardiac disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Electrocardiogram QT prolonged	Cardiac disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Left atrial dilatation	Cardiac disorders		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Left ventricular failure	Cardiac disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Mitral valve incompetence	Cardiac disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Pericardial effusion	Cardiac disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Sinus arrhythmia	Cardiac disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Ventricular extrasystoles	Cardiac disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Bundle branch block left	Cardiac disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Sinus tachycardia	Cardiac disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Pyloric stenosis	Congenital, familial and genetic disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Ear discomfort	Ear and labyrinth disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Ear pain	Ear and labyrinth disorders		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0023 affected255 at risk
Hypoacusis	Ear and labyrinth disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Vertigo	Ear and labyrinth disorders		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Tinnitus	Ear and labyrinth disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0023 affected255 at risk
Hypothyroidism	Endocrine disorders		Systematic Assessment	EG0009 affected228 at risk EG0011 affected114 at risk EG00245 affected255 at risk
Adrenal insufficiency	Endocrine disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Cushingoid	Endocrine disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Eye oedema	Eye disorders		Systematic Assessment	EG0005 affected228 at risk EG0010 affected114 at risk EG0025 affected255 at risk
Lacrimation increased	Eye disorders		Systematic Assessment	EG0004 affected228 at risk EG0011 affected114 at risk EG0022 affected255 at risk
Vision blurred	Eye disorders		Systematic Assessment	EG0003 affected228 at risk EG0011 affected114 at risk EG0025 affected255 at risk
Conjunctival haemorrhage	Eye disorders		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Conjunctivitis	Eye disorders		Systematic Assessment	EG0002 affected228 at risk EG0012 affected114 at risk EG0026 affected255 at risk
Visual disturbance	Eye disorders		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0024 affected255 at risk
Diplopia	Eye disorders		Systematic Assessment	EG0001 affected228 at risk EG0012 affected114 at risk EG0020 affected255 at risk
Eyelid oedema	Eye disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0029 affected255 at risk
Lacrimal disorder	Eye disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Photopsia	Eye disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Vitreous floaters	Eye disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Diarrhoea	Gastrointestinal disorders		Systematic Assessment	EG000102 affected228 at risk EG00121 affected114 at risk EG002119 affected255 at risk
Abdominal pain	Gastrointestinal disorders		Systematic Assessment	EG00082 affected228 at risk EG00137 affected114 at risk EG002106 affected255 at risk
Nausea	Gastrointestinal disorders		Systematic Assessment	EG00080 affected228 at risk EG00128 affected114 at risk EG002114 affected255 at risk
Vomiting	Gastrointestinal disorders		Systematic Assessment	EG00063 affected228 at risk EG00123 affected114 at risk EG00293 affected255 at risk
Constipation	Gastrointestinal disorders		Systematic Assessment	EG00053 affected228 at risk EG00122 affected114 at risk EG00275 affected255 at risk
Dyspepsia	Gastrointestinal disorders		Systematic Assessment	EG00045 affected228 at risk EG0016 affected114 at risk EG00256 affected255 at risk
Stomatitis	Gastrointestinal disorders		Systematic Assessment	EG00037 affected228 at risk EG0011 affected114 at risk EG00244 affected255 at risk
Abdominal pain upper	Gastrointestinal disorders		Systematic Assessment	EG00028 affected228 at risk EG00110 affected114 at risk EG00237 affected255 at risk
Dry mouth	Gastrointestinal disorders		Systematic Assessment	EG00026 affected228 at risk EG0014 affected114 at risk EG00222 affected255 at risk
Flatulence	Gastrointestinal disorders		Systematic Assessment	EG00024 affected228 at risk EG0015 affected114 at risk EG00226 affected255 at risk
Abdominal distension	Gastrointestinal disorders		Systematic Assessment	EG00018 affected228 at risk EG0019 affected114 at risk EG00238 affected255 at risk
Oral pain	Gastrointestinal disorders		Systematic Assessment	EG00016 affected228 at risk EG0011 affected114 at risk EG00230 affected255 at risk
Glossodynia	Gastrointestinal disorders		Systematic Assessment	EG00013 affected228 at risk EG0010 affected114 at risk EG00220 affected255 at risk
Gastrooesophageal reflux disease	Gastrointestinal disorders		Systematic Assessment	EG00010 affected228 at risk EG0012 affected114 at risk EG00223 affected255 at risk
Ascites	Gastrointestinal disorders		Systematic Assessment	EG0009 affected228 at risk EG0016 affected114 at risk EG0029 affected255 at risk
Abdominal discomfort	Gastrointestinal disorders		Systematic Assessment	EG0008 affected228 at risk EG0010 affected114 at risk EG00210 affected255 at risk
Rectal haemorrhage	Gastrointestinal disorders		Systematic Assessment	EG0008 affected228 at risk EG0012 affected114 at risk EG00216 affected255 at risk
Mouth ulceration	Gastrointestinal disorders		Systematic Assessment	EG0007 affected228 at risk EG0010 affected114 at risk EG0025 affected255 at risk
Dysphagia	Gastrointestinal disorders		Systematic Assessment	EG0006 affected228 at risk EG0011 affected114 at risk EG00212 affected255 at risk
Gastritis	Gastrointestinal disorders		Systematic Assessment	EG0004 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Gingival pain	Gastrointestinal disorders		Systematic Assessment	EG0004 affected228 at risk EG0011 affected114 at risk EG0023 affected255 at risk
Haemorrhoids	Gastrointestinal disorders		Systematic Assessment	EG0004 affected228 at risk EG0012 affected114 at risk EG00212 affected255 at risk
Oral discomfort	Gastrointestinal disorders		Systematic Assessment	EG0004 affected228 at risk EG0011 affected114 at risk EG0023 affected255 at risk
Abdominal pain lower	Gastrointestinal disorders		Systematic Assessment	EG0003 affected228 at risk EG0012 affected114 at risk EG0028 affected255 at risk
Eructation	Gastrointestinal disorders		Systematic Assessment	EG0003 affected228 at risk EG0012 affected114 at risk EG0025 affected255 at risk
Lip dry	Gastrointestinal disorders		Systematic Assessment	EG0003 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Oesophagitis	Gastrointestinal disorders		Systematic Assessment	EG0003 affected228 at risk EG0011 affected114 at risk EG0026 affected255 at risk
Oral mucosal discolouration	Gastrointestinal disorders		Systematic Assessment	EG0003 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Proctalgia	Gastrointestinal disorders		Systematic Assessment	EG0003 affected228 at risk EG0010 affected114 at risk EG0027 affected255 at risk
Reflux oesophagitis	Gastrointestinal disorders		Systematic Assessment	EG0003 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Retching	Gastrointestinal disorders		Systematic Assessment	EG0003 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Salivary hypersecretion	Gastrointestinal disorders		Systematic Assessment	EG0003 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Toothache	Gastrointestinal disorders		Systematic Assessment	EG0003 affected228 at risk EG0012 affected114 at risk EG0025 affected255 at risk
Duodenogastric reflux	Gastrointestinal disorders		Systematic Assessment	EG0002 affected228 at risk EG0011 affected114 at risk EG0022 affected255 at risk
Gastrointestinal haemorrhage	Gastrointestinal disorders		Systematic Assessment	EG0002 affected228 at risk EG0015 affected114 at risk EG0025 affected255 at risk
Gingival bleeding	Gastrointestinal disorders		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Glossitis	Gastrointestinal disorders		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0026 affected255 at risk
Haematochezia	Gastrointestinal disorders		Systematic Assessment	EG0002 affected228 at risk EG0012 affected114 at risk EG0024 affected255 at risk
Intestinal obstruction	Gastrointestinal disorders		Systematic Assessment	EG0002 affected228 at risk EG0011 affected114 at risk EG0022 affected255 at risk
Lip pain	Gastrointestinal disorders		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Lip ulceration	Gastrointestinal disorders		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Melaena	Gastrointestinal disorders		Systematic Assessment	EG0002 affected228 at risk EG0011 affected114 at risk EG0024 affected255 at risk
Painful defaecation	Gastrointestinal disorders		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Paraesthesia oral	Gastrointestinal disorders		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Small intestinal obstruction	Gastrointestinal disorders		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Stomach discomfort	Gastrointestinal disorders		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0024 affected255 at risk
Tongue blistering	Gastrointestinal disorders		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Aerophagia	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Anal fissure	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Anal fistula	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Anal inflammation	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Anorectal discomfort	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0024 affected255 at risk
Aphthous stomatitis	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Breath odour	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Chapped lips	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Cheilosis	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Colitis ulcerative	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Epigastric discomfort	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Faecal incontinence	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Gastric haemorrhage	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Gastric ulcer	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Gastritis haemorrhagic	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Gastrointestinal obstruction	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Gastrointestinal pain	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Gingival swelling	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Haematemesis	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0012 affected114 at risk EG0026 affected255 at risk
Haemorrhoidal haemorrhage	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Inguinal hernia	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Intestinal haemorrhage	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Lip swelling	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Loose tooth	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Mouth haemorrhage	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Odynophagia	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Oesophageal haemorrhage	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Oesophageal pain	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Oesophageal ulcer	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Periodontal disease	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Periodontitis	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Proctitis	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Rectal lesion	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Steatorrhoea	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Tooth discolouration	Gastrointestinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Enterovesical fistula	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Faeces discoloured	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Ileus	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0012 affected114 at risk EG0022 affected255 at risk
Pancreatitis acute	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Subileus	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Varices oesophageal	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Fatigue	General disorders		Systematic Assessment	EG000104 affected228 at risk EG00140 affected114 at risk EG002156 affected255 at risk
Asthenia	General disorders		Systematic Assessment	EG00051 affected228 at risk EG00111 affected114 at risk EG00262 affected255 at risk
Mucosal inflammation	General disorders		Systematic Assessment	EG00039 affected228 at risk EG0010 affected114 at risk EG00249 affected255 at risk
Pyrexia	General disorders		Systematic Assessment	EG00039 affected228 at risk EG00111 affected114 at risk EG00252 affected255 at risk
Oedema peripheral	General disorders		Systematic Assessment	EG00030 affected228 at risk EG00115 affected114 at risk EG00273 affected255 at risk
Oedema	General disorders		Systematic Assessment	EG00017 affected228 at risk EG0010 affected114 at risk EG00214 affected255 at risk
Chest pain	General disorders		Systematic Assessment	EG00010 affected228 at risk EG0015 affected114 at risk EG00217 affected255 at risk
Chills	General disorders		Systematic Assessment	EG0008 affected228 at risk EG0012 affected114 at risk EG0029 affected255 at risk
Disease progression	General disorders		Systematic Assessment	EG0008 affected228 at risk EG0014 affected114 at risk EG00233 affected255 at risk
Pain	General disorders		Systematic Assessment	EG0008 affected228 at risk EG0012 affected114 at risk EG00213 affected255 at risk
Face oedema	General disorders		Systematic Assessment	EG0003 affected228 at risk EG0010 affected114 at risk EG0029 affected255 at risk
Localised oedema	General disorders		Systematic Assessment	EG0003 affected228 at risk EG0010 affected114 at risk EG0024 affected255 at risk
Early satiety	General disorders		Systematic Assessment	EG0002 affected228 at risk EG0013 affected114 at risk EG0029 affected255 at risk
Influenza like illness	General disorders		Systematic Assessment	EG0002 affected228 at risk EG0012 affected114 at risk EG0025 affected255 at risk
Malaise	General disorders		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0026 affected255 at risk
Chest discomfort	General disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Discomfort	General disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Drug interaction	General disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Facial pain	General disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Gait disturbance	General disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
General physical health deterioration	General disorders		Systematic Assessment	EG0001 affected228 at risk EG0013 affected114 at risk EG0025 affected255 at risk
Infusion site reaction	General disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Multi-organ failure	General disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Performance status decreased	General disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Hepatic pain	Hepatobiliary disorders		Systematic Assessment	EG0003 affected228 at risk EG0011 affected114 at risk EG0026 affected255 at risk
Hyperbilirubinaemia	Hepatobiliary disorders		Systematic Assessment	EG0003 affected228 at risk EG0010 affected114 at risk EG0024 affected255 at risk
Jaundice	Hepatobiliary disorders		Systematic Assessment	EG0003 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Hepatomegaly	Hepatobiliary disorders		Systematic Assessment	EG0002 affected228 at risk EG0012 affected114 at risk EG0022 affected255 at risk
Acute hepatic failure	Hepatobiliary disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Bile duct stone	Hepatobiliary disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Cholangitis	Hepatobiliary disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Cholecystitis acute	Hepatobiliary disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Cholelithiasis	Hepatobiliary disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Cholestasis	Hepatobiliary disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Hepatic failure	Hepatobiliary disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Hepatic function abnormal	Hepatobiliary disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Hepatic haemorrhage	Hepatobiliary disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Portal hypertension	Hepatobiliary disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Hypersensitivity	Immune system disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Urinary tract infection	Infections and infestations		Systematic Assessment	EG00010 affected228 at risk EG0013 affected114 at risk EG00222 affected255 at risk
Influenza	Infections and infestations		Systematic Assessment	EG0008 affected228 at risk EG0012 affected114 at risk EG00213 affected255 at risk
Upper respiratory tract infection	Infections and infestations		Systematic Assessment	EG0006 affected228 at risk EG0011 affected114 at risk EG00218 affected255 at risk
Cystitis	Infections and infestations		Systematic Assessment	EG0005 affected228 at risk EG0012 affected114 at risk EG0023 affected255 at risk
Infection	Infections and infestations		Systematic Assessment	EG0004 affected228 at risk EG0010 affected114 at risk EG0026 affected255 at risk
Nasopharyngitis	Infections and infestations		Systematic Assessment	EG0004 affected228 at risk EG0013 affected114 at risk EG00211 affected255 at risk
Oral herpes	Infections and infestations		Systematic Assessment	EG0004 affected228 at risk EG0011 affected114 at risk EG0024 affected255 at risk
Sinusitis	Infections and infestations		Systematic Assessment	EG0004 affected228 at risk EG0011 affected114 at risk EG0028 affected255 at risk
Bronchitis	Infections and infestations		Systematic Assessment	EG0003 affected228 at risk EG0011 affected114 at risk EG0022 affected255 at risk
Tooth abscess	Infections and infestations		Systematic Assessment	EG0003 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Tooth infection	Infections and infestations		Systematic Assessment	EG0003 affected228 at risk EG0011 affected114 at risk EG0024 affected255 at risk
Central line infection	Infections and infestations		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Folliculitis	Infections and infestations		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0025 affected255 at risk
Gastroenteritis	Infections and infestations		Systematic Assessment	EG0002 affected228 at risk EG0011 affected114 at risk EG00211 affected255 at risk
Nail infection	Infections and infestations		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Abscess limb	Infections and infestations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Bacteraemia	Infections and infestations		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0022 affected255 at risk
Catheter sepsis	Infections and infestations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Furuncle	Infections and infestations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Gastroenteritis viral	Infections and infestations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Gingival abscess	Infections and infestations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Gingival infection	Infections and infestations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Herpes zoster	Infections and infestations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0025 affected255 at risk
Lobar pneumonia	Infections and infestations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Localised infection	Infections and infestations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Lower respiratory tract infection	Infections and infestations		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0026 affected255 at risk
Mediastinitis	Infections and infestations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Nipple infection	Infections and infestations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Oral candidiasis	Infections and infestations		Systematic Assessment	EG0001 affected228 at risk EG0013 affected114 at risk EG0023 affected255 at risk
Oral fungal infection	Infections and infestations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Oral infection	Infections and infestations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Pilonidal cyst	Infections and infestations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Pneumonia	Infections and infestations		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0025 affected255 at risk
Sinusitis bacterial	Infections and infestations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Skin infection	Infections and infestations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Staphylococcal infection	Infections and infestations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Staphylococcal sepsis	Infections and infestations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Subcutaneous abscess	Infections and infestations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Tinea infection	Infections and infestations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Tinea pedis	Infections and infestations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Tonsillitis	Infections and infestations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Viral infection	Infections and infestations		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Viral oesophagitis	Infections and infestations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Wound infection	Infections and infestations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Arthritis infective	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Laryngitis	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0022 affected255 at risk
Postoperative wound infection	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0022 affected255 at risk
Contusion	Injury, poisoning and procedural complications		Systematic Assessment	EG0009 affected228 at risk EG0011 affected114 at risk EG0029 affected255 at risk
Procedural pain	Injury, poisoning and procedural complications		Systematic Assessment	EG0003 affected228 at risk EG0011 affected114 at risk EG0022 affected255 at risk
Back injury	Injury, poisoning and procedural complications		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0022 affected255 at risk
Excoriation	Injury, poisoning and procedural complications		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Medical device pain	Injury, poisoning and procedural complications		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Periorbital haematoma	Injury, poisoning and procedural complications		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Procedural site reaction	Injury, poisoning and procedural complications		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Radiation oesophagitis	Injury, poisoning and procedural complications		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Spinal compression fracture	Injury, poisoning and procedural complications		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Spinal fracture	Injury, poisoning and procedural complications		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Sunburn	Injury, poisoning and procedural complications		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Wound dehiscence	Injury, poisoning and procedural complications		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Fall	Injury, poisoning and procedural complications		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0023 affected255 at risk
Hepatic haematoma	Injury, poisoning and procedural complications		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Injury	Injury, poisoning and procedural complications		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Overdose	Injury, poisoning and procedural complications		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Weight decreased	Investigations		Systematic Assessment	EG00014 affected228 at risk EG0016 affected114 at risk EG00245 affected255 at risk
Platelet count decreased	Investigations		Systematic Assessment	EG0009 affected228 at risk EG0010 affected114 at risk EG00213 affected255 at risk
Blood creatinine increased	Investigations		Systematic Assessment	EG0007 affected228 at risk EG0011 affected114 at risk EG00220 affected255 at risk
Haemoglobin decreased	Investigations		Systematic Assessment	EG0007 affected228 at risk EG0011 affected114 at risk EG00211 affected255 at risk
Lipase increased	Investigations		Systematic Assessment	EG0006 affected228 at risk EG0013 affected114 at risk EG0028 affected255 at risk
Blood amylase increased	Investigations		Systematic Assessment	EG0005 affected228 at risk EG0012 affected114 at risk EG0026 affected255 at risk
Blood bilirubin increased	Investigations		Systematic Assessment	EG0005 affected228 at risk EG0012 affected114 at risk EG0023 affected255 at risk
White blood cell count decreased	Investigations		Systematic Assessment	EG0005 affected228 at risk EG0010 affected114 at risk EG00212 affected255 at risk
Blood alkaline phosphatase increased	Investigations		Systematic Assessment	EG0004 affected228 at risk EG0012 affected114 at risk EG00210 affected255 at risk
Blood creatine phosphokinase increased	Investigations		Systematic Assessment	EG0004 affected228 at risk EG0011 affected114 at risk EG0022 affected255 at risk
Alanine aminotransferase increased	Investigations		Systematic Assessment	EG0003 affected228 at risk EG0013 affected114 at risk EG0028 affected255 at risk
Aspartate aminotransferase increased	Investigations		Systematic Assessment	EG0003 affected228 at risk EG0011 affected114 at risk EG0029 affected255 at risk
Neutrophil count decreased	Investigations		Systematic Assessment	EG0003 affected228 at risk EG0010 affected114 at risk EG00211 affected255 at risk
Urine output decreased	Investigations		Systematic Assessment	EG0003 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Activated partial thromboplastin time prolonged	Investigations		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
International normalised ratio increased	Investigations		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Prothrombin time prolonged	Investigations		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Alanine aminotransferase abnormal	Investigations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Ammonia increased	Investigations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Aspartate aminotransferase abnormal	Investigations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Blood alkaline phosphatase abnormal	Investigations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Blood bicarbonate decreased	Investigations		Systematic Assessment	EG0001 affected228 at risk EG0012 affected114 at risk EG0022 affected255 at risk
Blood bilirubin	Investigations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Blood creatine phosphokinase	Investigations		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0023 affected255 at risk
Blood creatinine	Investigations		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Blood magnesium decreased	Investigations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Blood potassium increased	Investigations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Blood pressure increased	Investigations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Blood thyroid stimulating hormone increased	Investigations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Blood urea increased	Investigations		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0023 affected255 at risk
Blood urine present	Investigations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Haemoglobin	Investigations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Heart rate increased	Investigations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Neutrophil count	Investigations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Neutrophil count normal	Investigations		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Oxygen saturation decreased	Investigations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Transaminases increased	Investigations		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Blood glucose increased	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0023 affected255 at risk
Blood sodium increased	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Breath sounds abnormal	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Cardiac murmur	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Electrocardiogram abnormal	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Heart rate irregular	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Occult blood positive	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Pancreatic enzymes increased	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0012 affected114 at risk EG0021 affected255 at risk
Platelet count increased	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0022 affected255 at risk
Anorexia	Metabolism and nutrition disorders		Systematic Assessment	EG00076 affected228 at risk EG00119 affected114 at risk EG00292 affected255 at risk
Decreased appetite	Metabolism and nutrition disorders		Systematic Assessment	EG00010 affected228 at risk EG0015 affected114 at risk EG00225 affected255 at risk
Hypokalaemia	Metabolism and nutrition disorders		Systematic Assessment	EG00010 affected228 at risk EG0011 affected114 at risk EG00213 affected255 at risk
Dehydration	Metabolism and nutrition disorders		Systematic Assessment	EG0009 affected228 at risk EG0010 affected114 at risk EG00219 affected255 at risk
Hypoalbuminaemia	Metabolism and nutrition disorders		Systematic Assessment	EG0006 affected228 at risk EG0011 affected114 at risk EG00211 affected255 at risk
Hyperglycaemia	Metabolism and nutrition disorders		Systematic Assessment	EG0004 affected228 at risk EG0010 affected114 at risk EG00210 affected255 at risk
Hypocalcaemia	Metabolism and nutrition disorders		Systematic Assessment	EG0004 affected228 at risk EG0011 affected114 at risk EG0024 affected255 at risk
Hypoglycaemia	Metabolism and nutrition disorders		Systematic Assessment	EG0004 affected228 at risk EG0011 affected114 at risk EG0026 affected255 at risk
Hyponatraemia	Metabolism and nutrition disorders		Systematic Assessment	EG0003 affected228 at risk EG0012 affected114 at risk EG0024 affected255 at risk
Hypercholesterolaemia	Metabolism and nutrition disorders		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0024 affected255 at risk
Hyperuricaemia	Metabolism and nutrition disorders		Systematic Assessment	EG0002 affected228 at risk EG0011 affected114 at risk EG0023 affected255 at risk
Food intolerance	Metabolism and nutrition disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Hypercalcaemia	Metabolism and nutrition disorders		Systematic Assessment	EG0001 affected228 at risk EG0012 affected114 at risk EG0022 affected255 at risk
Hyperkalaemia	Metabolism and nutrition disorders		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Hyperphosphataemia	Metabolism and nutrition disorders		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Hypertriglyceridaemia	Metabolism and nutrition disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0024 affected255 at risk
Hypophosphataemia	Metabolism and nutrition disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0024 affected255 at risk
Hypoproteinaemia	Metabolism and nutrition disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Metabolic acidosis	Metabolism and nutrition disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Acidosis	Metabolism and nutrition disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Appetite disorder	Metabolism and nutrition disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Gout	Metabolism and nutrition disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0022 affected255 at risk
Increased appetite	Metabolism and nutrition disorders		Systematic Assessment	EG0000 affected228 at risk EG0012 affected114 at risk EG0021 affected255 at risk
Malnutrition	Metabolism and nutrition disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Back pain	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG00031 affected228 at risk EG00114 affected114 at risk EG00251 affected255 at risk
Pain in extremity	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG00028 affected228 at risk EG0014 affected114 at risk EG00246 affected255 at risk
Arthralgia	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG00023 affected228 at risk EG0018 affected114 at risk EG00251 affected255 at risk
Muscle spasms	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG00015 affected228 at risk EG0015 affected114 at risk EG00227 affected255 at risk
Myalgia	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG00015 affected228 at risk EG0014 affected114 at risk EG00225 affected255 at risk
Flank pain	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0009 affected228 at risk EG0010 affected114 at risk EG00210 affected255 at risk
Musculoskeletal pain	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0009 affected228 at risk EG0015 affected114 at risk EG00228 affected255 at risk
Muscular weakness	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0007 affected228 at risk EG0011 affected114 at risk EG00211 affected255 at risk
Neck pain	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0006 affected228 at risk EG0012 affected114 at risk EG00212 affected255 at risk
Bone pain	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0005 affected228 at risk EG0012 affected114 at risk EG0029 affected255 at risk
Musculoskeletal stiffness	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0004 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Joint stiffness	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0024 affected255 at risk
Limb discomfort	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0024 affected255 at risk
Musculoskeletal chest pain	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0002 affected228 at risk EG0013 affected114 at risk EG0025 affected255 at risk
Pain in jaw	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Exostosis	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Fistula	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Groin pain	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0001 affected228 at risk EG0013 affected114 at risk EG0025 affected255 at risk
Intervertebral disc disorder	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Joint effusion	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Joint range of motion decreased	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Muscle tightness	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Muscle twitching	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Osteoporosis	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Tendonitis	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0022 affected255 at risk
Costochondritis	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Intervertebral disc protrusion	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Mobility decreased	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Rheumatoid arthritis	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Tumour haemorrhage	Neoplasms benign, malignant and unspecified (incl cysts and polyps)		Systematic Assessment	EG0003 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Basal cell carcinoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Haemangioma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Haemorrhagic tumour necrosis	Neoplasms benign, malignant and unspecified (incl cysts and polyps)		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Multiple myeloma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Neoplasm	Neoplasms benign, malignant and unspecified (incl cysts and polyps)		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Tumour associated fever	Neoplasms benign, malignant and unspecified (incl cysts and polyps)		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Tumour lysis syndrome	Neoplasms benign, malignant and unspecified (incl cysts and polyps)		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Tumour pain	Neoplasms benign, malignant and unspecified (incl cysts and polyps)		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0026 affected255 at risk
Vascular neoplasm	Neoplasms benign, malignant and unspecified (incl cysts and polyps)		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Cancer pain	Neoplasms benign, malignant and unspecified (incl cysts and polyps)		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Neoplasm progression	Neoplasms benign, malignant and unspecified (incl cysts and polyps)		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Dysgeusia	Nervous system disorders		Systematic Assessment	EG00054 affected228 at risk EG0013 affected114 at risk EG00257 affected255 at risk
Headache	Nervous system disorders		Systematic Assessment	EG00048 affected228 at risk EG00118 affected114 at risk EG00267 affected255 at risk
Dizziness	Nervous system disorders		Systematic Assessment	EG00022 affected228 at risk EG0017 affected114 at risk EG00231 affected255 at risk
Paraesthesia	Nervous system disorders		Systematic Assessment	EG00011 affected228 at risk EG0011 affected114 at risk EG00216 affected255 at risk
Hypoaesthesia	Nervous system disorders		Systematic Assessment	EG0008 affected228 at risk EG0014 affected114 at risk EG00212 affected255 at risk
Neuropathy peripheral	Nervous system disorders		Systematic Assessment	EG0007 affected228 at risk EG0012 affected114 at risk EG0028 affected255 at risk
Ageusia	Nervous system disorders		Systematic Assessment	EG0006 affected228 at risk EG0010 affected114 at risk EG0025 affected255 at risk
Peripheral sensory neuropathy	Nervous system disorders		Systematic Assessment	EG0005 affected228 at risk EG0012 affected114 at risk EG0025 affected255 at risk
Sciatica	Nervous system disorders		Systematic Assessment	EG0004 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Somnolence	Nervous system disorders		Systematic Assessment	EG0004 affected228 at risk EG0012 affected114 at risk EG0029 affected255 at risk
Balance disorder	Nervous system disorders		Systematic Assessment	EG0003 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Hyperaesthesia	Nervous system disorders		Systematic Assessment	EG0003 affected228 at risk EG0011 affected114 at risk EG0023 affected255 at risk
Lethargy	Nervous system disorders		Systematic Assessment	EG0003 affected228 at risk EG0011 affected114 at risk EG0029 affected255 at risk
Syncope	Nervous system disorders		Systematic Assessment	EG0003 affected228 at risk EG0011 affected114 at risk EG0023 affected255 at risk
Tremor	Nervous system disorders		Systematic Assessment	EG0003 affected228 at risk EG0011 affected114 at risk EG0025 affected255 at risk
Dizziness postural	Nervous system disorders		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Memory impairment	Nervous system disorders		Systematic Assessment	EG0002 affected228 at risk EG0011 affected114 at risk EG0024 affected255 at risk
Migraine	Nervous system disorders		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Parosmia	Nervous system disorders		Systematic Assessment	EG0002 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Sinus headache	Nervous system disorders		Systematic Assessment	EG0002 affected228 at risk EG0011 affected114 at risk EG0025 affected255 at risk
Amnesia	Nervous system disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Ataxia	Nervous system disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Cerebral ischaemia	Nervous system disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Depressed level of consciousness	Nervous system disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Diabetic neuropathy	Nervous system disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Disturbance in attention	Nervous system disorders		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0022 affected255 at risk
Encephalopathy	Nervous system disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Facial palsy	Nervous system disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Head discomfort	Nervous system disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Myoclonus	Nervous system disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Peripheral motor neuropathy	Nervous system disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Restless legs syndrome	Nervous system disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Sensory disturbance	Nervous system disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Syncope vasovagal	Nervous system disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Transient ischaemic attack	Nervous system disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Burning sensation	Nervous system disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Cerebrovascular accident	Nervous system disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Coma	Nervous system disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Hemicephalalgia	Nervous system disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Neuralgia	Nervous system disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Paralysis	Nervous system disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Insomnia	Psychiatric disorders		Systematic Assessment	EG00025 affected228 at risk EG00111 affected114 at risk EG00234 affected255 at risk
Anxiety	Psychiatric disorders		Systematic Assessment	EG0007 affected228 at risk EG0012 affected114 at risk EG00211 affected255 at risk
Depression	Psychiatric disorders		Systematic Assessment	EG0007 affected228 at risk EG0012 affected114 at risk EG00223 affected255 at risk
Agitation	Psychiatric disorders		Systematic Assessment	EG0002 affected228 at risk EG0011 affected114 at risk EG0027 affected255 at risk
Confusional state	Psychiatric disorders		Systematic Assessment	EG0002 affected228 at risk EG0012 affected114 at risk EG00214 affected255 at risk
Nervousness	Psychiatric disorders		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0022 affected255 at risk
Sleep disorder	Psychiatric disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Depressed mood	Psychiatric disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Chromaturia	Renal and urinary disorders		Systematic Assessment	EG00012 affected228 at risk EG0012 affected114 at risk EG0026 affected255 at risk
Dysuria	Renal and urinary disorders		Systematic Assessment	EG00010 affected228 at risk EG0011 affected114 at risk EG00212 affected255 at risk
Haematuria	Renal and urinary disorders		Systematic Assessment	EG0006 affected228 at risk EG0012 affected114 at risk EG0028 affected255 at risk
Urinary retention	Renal and urinary disorders		Systematic Assessment	EG0004 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Hydronephrosis	Renal and urinary disorders		Systematic Assessment	EG0003 affected228 at risk EG0013 affected114 at risk EG0026 affected255 at risk
Pollakiuria	Renal and urinary disorders		Systematic Assessment	EG0003 affected228 at risk EG0014 affected114 at risk EG00211 affected255 at risk
Polyuria	Renal and urinary disorders		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Proteinuria	Renal and urinary disorders		Systematic Assessment	EG0002 affected228 at risk EG0011 affected114 at risk EG0023 affected255 at risk
Bladder pain	Renal and urinary disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Choluria	Renal and urinary disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Nephrotic syndrome	Renal and urinary disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Nocturia	Renal and urinary disorders		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0022 affected255 at risk
Oliguria	Renal and urinary disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Renal colic	Renal and urinary disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Renal failure	Renal and urinary disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Renal failure acute	Renal and urinary disorders		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0022 affected255 at risk
Urine odour abnormal	Renal and urinary disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Bladder spasm	Renal and urinary disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0022 affected255 at risk
Hydroureter	Renal and urinary disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0022 affected255 at risk
Micturition urgency	Renal and urinary disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0023 affected255 at risk
Ureteric obstruction	Renal and urinary disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Urethral stenosis	Renal and urinary disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0022 affected255 at risk
Urinary incontinence	Renal and urinary disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0023 affected255 at risk
Gynaecomastia	Reproductive system and breast disorders		Systematic Assessment	EG0004 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Pelvic pain	Reproductive system and breast disorders		Systematic Assessment	EG0004 affected228 at risk EG0013 affected114 at risk EG00211 affected255 at risk
Oedema genital	Reproductive system and breast disorders		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Atrophic vulvovaginitis	Reproductive system and breast disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Genital discomfort	Reproductive system and breast disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Genital pain	Reproductive system and breast disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Genital rash	Reproductive system and breast disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Menstruation delayed	Reproductive system and breast disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Metrorrhagia	Reproductive system and breast disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Nipple pain	Reproductive system and breast disorders		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Pelvic discomfort	Reproductive system and breast disorders		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0022 affected255 at risk
Vaginal erythema	Reproductive system and breast disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Vaginal haemorrhage	Reproductive system and breast disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0024 affected255 at risk
Vaginal pain	Reproductive system and breast disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Vulval ulceration	Reproductive system and breast disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Vulvovaginal burning sensation	Reproductive system and breast disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Benign prostatic hyperplasia	Reproductive system and breast disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Breast mass	Reproductive system and breast disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0022 affected255 at risk
Breast pain	Reproductive system and breast disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Perineal pain	Reproductive system and breast disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Prostatitis	Reproductive system and breast disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0022 affected255 at risk
Dyspnoea	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG00025 affected228 at risk EG00116 affected114 at risk EG00256 affected255 at risk
Epistaxis	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG00022 affected228 at risk EG0010 affected114 at risk EG00227 affected255 at risk
Cough	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG00019 affected228 at risk EG00114 affected114 at risk EG00243 affected255 at risk
Pharyngolaryngeal pain	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0009 affected228 at risk EG0013 affected114 at risk EG00217 affected255 at risk
Hiccups	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0004 affected228 at risk EG0011 affected114 at risk EG0026 affected255 at risk
Pleural effusion	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0004 affected228 at risk EG0011 affected114 at risk EG0027 affected255 at risk
Pulmonary embolism	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0004 affected228 at risk EG0013 affected114 at risk EG0025 affected255 at risk
Rhinorrhoea	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0004 affected228 at risk EG0010 affected114 at risk EG0027 affected255 at risk
Dysphonia	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0003 affected228 at risk EG0011 affected114 at risk EG0023 affected255 at risk
Dry throat	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Dyspnoea exertional	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0002 affected228 at risk EG0012 affected114 at risk EG0029 affected255 at risk
Nasal discomfort	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0025 affected255 at risk
Productive cough	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0002 affected228 at risk EG0011 affected114 at risk EG0024 affected255 at risk
Atelectasis	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Dyspnoea paroxysmal nocturnal	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Hypoxia	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Nasal congestion	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Nasal disorder	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Nasal dryness	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0026 affected255 at risk
Nasal mucosal disorder	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Nasal ulcer	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Painful respiration	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Pharyngeal inflammation	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Pharyngeal oedema	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Pharyngolaryngeal discomfort	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Pneumothorax	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Pulmonary hypertension	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Pulmonary thrombosis	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Rales	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Rhinitis allergic	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Throat irritation	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Pneumonia aspiration	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Pulmonary congestion	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Respiratory tract congestion	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Sinus congestion	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0024 affected255 at risk
Sinus disorder	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Wheezing	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Skin discolouration	Skin and subcutaneous tissue disorders		Systematic Assessment	EG00064 affected228 at risk EG0017 affected114 at risk EG00277 affected255 at risk
Rash	Skin and subcutaneous tissue disorders		Systematic Assessment	EG00040 affected228 at risk EG0017 affected114 at risk EG00248 affected255 at risk
Palmar-plantar erythrodysaesthesia syndrome	Skin and subcutaneous tissue disorders		Systematic Assessment	EG00025 affected228 at risk EG0011 affected114 at risk EG00256 affected255 at risk
Hair colour changes	Skin and subcutaneous tissue disorders		Systematic Assessment	EG00019 affected228 at risk EG0012 affected114 at risk EG00250 affected255 at risk
Dry skin	Skin and subcutaneous tissue disorders		Systematic Assessment	EG00017 affected228 at risk EG0013 affected114 at risk EG00233 affected255 at risk
Alopecia	Skin and subcutaneous tissue disorders		Systematic Assessment	EG00014 affected228 at risk EG0011 affected114 at risk EG00222 affected255 at risk
Skin reaction	Skin and subcutaneous tissue disorders		Systematic Assessment	EG00013 affected228 at risk EG0010 affected114 at risk EG00222 affected255 at risk
Pruritus	Skin and subcutaneous tissue disorders		Systematic Assessment	EG00011 affected228 at risk EG0014 affected114 at risk EG00221 affected255 at risk
Erythema	Skin and subcutaneous tissue disorders		Systematic Assessment	EG00010 affected228 at risk EG0013 affected114 at risk EG00218 affected255 at risk
Eczema	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0008 affected228 at risk EG0012 affected114 at risk EG00214 affected255 at risk
Night sweats	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0008 affected228 at risk EG0013 affected114 at risk EG00210 affected255 at risk
Periorbital oedema	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0008 affected228 at risk EG0010 affected114 at risk EG00213 affected255 at risk
Skin hyperpigmentation	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0008 affected228 at risk EG0010 affected114 at risk EG0028 affected255 at risk
Dermatitis	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0006 affected228 at risk EG0010 affected114 at risk EG0026 affected255 at risk
Hyperhidrosis	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0005 affected228 at risk EG0013 affected114 at risk EG0028 affected255 at risk
Skin exfoliation	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0005 affected228 at risk EG0010 affected114 at risk EG0028 affected255 at risk
Blister	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0004 affected228 at risk EG0010 affected114 at risk EG0029 affected255 at risk
Ecchymosis	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0004 affected228 at risk EG0010 affected114 at risk EG0026 affected255 at risk
Hyperkeratosis	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0004 affected228 at risk EG0010 affected114 at risk EG00210 affected255 at risk
Petechiae	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0004 affected228 at risk EG0010 affected114 at risk EG0025 affected255 at risk
Skin fissures	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0004 affected228 at risk EG0010 affected114 at risk EG0028 affected255 at risk
Acne	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0003 affected228 at risk EG0010 affected114 at risk EG0024 affected255 at risk
Nail disorder	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0003 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Skin lesion	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0003 affected228 at risk EG0011 affected114 at risk EG0029 affected255 at risk
Dermatitis acneiform	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0002 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Dermatitis exfoliative	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Increased tendency to bruise	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Nail discolouration	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Pigmentation disorder	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0024 affected255 at risk
Rash erythematous	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Rash macular	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0002 affected228 at risk EG0011 affected114 at risk EG0022 affected255 at risk
Urticaria	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0002 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Acrodermatitis	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0025 affected255 at risk
Cold sweat	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0001 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Dermal cyst	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Diabetic ulcer	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Erythema nodosum	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Madarosis	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Pain of skin	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Palmar erythema	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Plantar erythema	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Rash generalised	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Skin atrophy	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Skin depigmentation	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Skin hypopigmentation	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Skin toxicity	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Skin ulcer	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Swelling face	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Dermatitis allergic	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Onychoclasis	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Pruritus generalised	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Skin irritation	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0023 affected255 at risk
Subcutaneous nodule	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0022 affected255 at risk
Telangiectasia	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0022 affected255 at risk
Skin lesion excision	Surgical and medical procedures		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Pneumatic compression therapy	Surgical and medical procedures		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0021 affected255 at risk
Hypertension	Vascular disorders		Systematic Assessment	EG00040 affected228 at risk EG0019 affected114 at risk EG00271 affected255 at risk
Hot flush	Vascular disorders		Systematic Assessment	EG0009 affected228 at risk EG0013 affected114 at risk EG0027 affected255 at risk
Deep vein thrombosis	Vascular disorders		Systematic Assessment	EG0004 affected228 at risk EG0010 affected114 at risk EG0025 affected255 at risk
Hypotension	Vascular disorders		Systematic Assessment	EG0003 affected228 at risk EG0011 affected114 at risk EG0026 affected255 at risk
Pallor	Vascular disorders		Systematic Assessment	EG0003 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Haemorrhage	Vascular disorders		Systematic Assessment	EG0002 affected228 at risk EG0011 affected114 at risk EG0022 affected255 at risk
Hypertensive crisis	Vascular disorders		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Vasculitis	Vascular disorders		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Venous thrombosis limb	Vascular disorders		Systematic Assessment	EG0002 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Lymphoedema	Vascular disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Orthostatic hypotension	Vascular disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Systolic hypertension	Vascular disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Thrombosis	Vascular disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0020 affected255 at risk
Vasodilatation	Vascular disorders		Systematic Assessment	EG0001 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Circulatory collapse	Vascular disorders		Systematic Assessment	EG0000 affected228 at risk EG0011 affected114 at risk EG0020 affected255 at risk
Disseminated intravascular coagulation	Blood and lymphatic system disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Granulocytopenia	Blood and lymphatic system disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
haemolytic anaemia	Blood and lymphatic system disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Leukocytosis	Blood and lymphatic system disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Cardiac failure congestive	Cardiac disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Cardio-respiratory arrest	Cardiac disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Sinus bradycardia	Cardiac disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Ventricular hypokinesia	Cardiac disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Left ventricular hypertrophy	Cardiac disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Myocardial infarction	Cardiac disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Myocardial ischaemia	Cardiac disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Splinter haemorhages	Cardiac disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Supraventricular tachycardia	Cardiac disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Ventricular dysfunction	Cardiac disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Dermoid cyst	Congenital, familial and genetic disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Epidermolysis	Congenital, familial and genetic disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Hydrocele	Congenital, familial and genetic disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Dysacusis	Ear and labyrinth disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Hearing impaired	Ear and labyrinth disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Hyperthyroidism	Endocrine disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Thyroid disorder	Endocrine disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Eye pain	Eye disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Eye pruritus	Eye disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Dry eye	Eye disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Glaucoma	Eye disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Macular degeneration	Eye disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Orbital oedema	Eye disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Asthenopia	Eye disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Blepharitis	Eye disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Eye discharge	Eye disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Eye haemorrhage	Eye disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Eye irritation	Eye disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Eye swelling	Eye disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Ocular hyperaemia	Eye disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Punctate keratitis	Eye disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Scleral haemorrhage	Eye disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Visual acuity reduced	Eye disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Abdominal tenderness	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Hiatus hernia	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Anal haemorrhage	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Gingivitis	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Peritoneal haemorrhage	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Rectal tenesmus	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Upper gastrointestinal haemorrhage	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Abdominal hernia	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Abdominal mass	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Abdominal rigidity	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Defaecation urgency	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Dental caries	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Diverticulum	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Duodenal fistula	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Duodenal ulcer	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Enamel anomaly	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Enterocutaneous fistula	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Gastrointestinal disorder	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Gastrointestinal motility disorder	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Gastrointestinal sounds abnormal	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Hyperchlorhydria	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Hypoaesthesia oral	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Intra-abdominal haemorrhage	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Large intestinal haemorrhage	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Salivary gland enlargement	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Sensitivity of teeth	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Swollen tongue	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Tongue disorder	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Tongue haemorrhage	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Tongue spasm	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Tongue ulceration	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Tooth erosion	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Umbilical hernia	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Feeling hot	General disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Ill-defined disorder	General disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Impaired healing	General disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Catheter related complication	General disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Catheter site discharge	General disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Catheter site excoriation	General disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Catheter site pain	General disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Cyst	General disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Effusion	General disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Feeling cold	General disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Hernia pain	General disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Infusion site extravasation	General disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Irritability	General disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Mucosal dryness	General disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Necrosis	General disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Peripheral coldness	General disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Pneumatosis	General disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Thirst	General disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Ulcer haemorrhage	General disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Xerosis	General disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Hepatotoxicity	Hepatobiliary disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Portal vein thrombosis	Hepatobiliary disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Cholecystitis	Hepatobiliary disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Foetor hepaticus	Hepatobiliary disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Seasonal allergy	Immune system disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Respiratory tract infection	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0025 affected255 at risk
Rhinitis	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0026 affected255 at risk
Cellulitis	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Ear infection	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Pharyngitis	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Sepsis	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Abdominal abscess	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Anal infection	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Bacterial infection	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Campylobacter infection	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Diverticulitis	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Empyema	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Fungal infection	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Gastrointestinal infection	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Genital herpes	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Herpes simplex	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Infected skin ulcer	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Liver abscess	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Lung infection	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Necrotising ulcerative gingivostomatitis	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Oesophageal candidiasis	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Orchitis	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Osteomyelitis	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Otitis media	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Perirectal abscess	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Proctitis monilial	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Pyelonephritis	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Urinary tract infection fungal	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Urosepsis	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Viral upper respiratory tract infection	Infections and infestations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Skin laceration	Injury, poisoning and procedural complications		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0024 affected255 at risk
Thermal burn	Injury, poisoning and procedural complications		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Wound	Injury, poisoning and procedural complications		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Anal injury	Injury, poisoning and procedural complications		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Device malfunction	Injury, poisoning and procedural complications		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Feeding tube complication	Injury, poisoning and procedural complications		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Joint sprain	Injury, poisoning and procedural complications		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Ligament rupture	Injury, poisoning and procedural complications		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Limb injury	Injury, poisoning and procedural complications		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Medical device complication	Injury, poisoning and procedural complications		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Medical device site reaction	Injury, poisoning and procedural complications		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Medication error	Injury, poisoning and procedural complications		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Muscle strain	Injury, poisoning and procedural complications		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Neck injury	Injury, poisoning and procedural complications		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Post gastric surgery syndrome	Injury, poisoning and procedural complications		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Post procedural diarrhoea	Injury, poisoning and procedural complications		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Postoperative constipation	Injury, poisoning and procedural complications		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Postoperative fever	Injury, poisoning and procedural complications		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Skeletal injury	Injury, poisoning and procedural complications		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Weight increased	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0026 affected255 at risk
Blood lactate dehydrogenase increased	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0025 affected255 at risk
Blood potassium decreased	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0024 affected255 at risk
Blood uric acid increased	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0024 affected255 at risk
Blood albumin decreased	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Liver function test abnormal	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Platelet count	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Bacterial culture positive	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Blood alkaline phosphatase	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Blood calcium decreased	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Blood glucose decreased	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Blood phosphorus decreased	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
C-reactive protein increased	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
ECG signs of myocardial ischaemia	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Electrocardiogram ST segment depression	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Gamma-glutamyltransferase increased	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Hepatic enzyme increased	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Lymph node palpable	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Lymphocyte count decreased	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Mean cell volume increased	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Multiple gated acquisition scan abnormal	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Venous pressure jugular increased	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Vitamin B12 decreased	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
White blood cell count	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
White blood cell count increased	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Hypomagnesaemia	Metabolism and nutrition disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0025 affected255 at risk
Cachexia	Metabolism and nutrition disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Cow's milk intolerance	Metabolism and nutrition disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Fluid retention	Metabolism and nutrition disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Hypochloraemia	Metabolism and nutrition disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Iron deficiency	Metabolism and nutrition disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Lactose intolerance	Metabolism and nutrition disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Polydipsia	Metabolism and nutrition disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Arthritis	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Joint swelling	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Muscle contracture	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Musculoskeletal discomfort	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Myopathy	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Rotator cuff syndrome	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Sensation of heaviness	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Spinal osteoarthritis	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Tendon disorder	Musculoskeletal and connective tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Metastases to liver	Neoplasms benign, malignant and unspecified (incl cysts and polyps)		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Anal neoplasm	Neoplasms benign, malignant and unspecified (incl cysts and polyps)		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Hepatic neoplasm malignant	Neoplasms benign, malignant and unspecified (incl cysts and polyps)		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Metastases to bone	Neoplasms benign, malignant and unspecified (incl cysts and polyps)		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Neurilemmoma benign	Neoplasms benign, malignant and unspecified (incl cysts and polyps)		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Tumour perforation	Neoplasms benign, malignant and unspecified (incl cysts and polyps)		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Hepatic encephalopathy	Nervous system disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0025 affected255 at risk
Dysarthria	Nervous system disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Loss of consciousness	Nervous system disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Aphonia	Nervous system disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Asterixis	Nervous system disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Carotid artery disease	Nervous system disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Cerebral haemorrhage	Nervous system disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Cervical root pain	Nervous system disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Convulsion	Nervous system disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Dysaesthesia	Nervous system disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Guillain-barre syndrome	Nervous system disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Hemiparesis	Nervous system disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Hypogeusia	Nervous system disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Intention tremor	Nervous system disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Intracranial venous sinus thrombosis	Nervous system disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Lacunar infarction	Nervous system disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Migraine with aura	Nervous system disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Movement disorder	Nervous system disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Petit mal epilepsy	Nervous system disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Mood altered	Psychiatric disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Abnormal dreams	Psychiatric disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Apathy	Psychiatric disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Completed suicide	Psychiatric disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Dysphemia	Psychiatric disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Emotional disorder	Psychiatric disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Hallucination	Psychiatric disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Psychomotor retardation	Psychiatric disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Psychotic disorder	Psychiatric disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Renal impairment	Renal and urinary disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Focal segmental glomerulosclerosis	Renal and urinary disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Obstructive uropathy	Renal and urinary disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Renal cyst	Renal and urinary disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Residual urine	Renal and urinary disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Scrotal oedema	Reproductive system and breast disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Erectile dysfunction	Reproductive system and breast disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Genital haemorrhage	Reproductive system and breast disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Genital lesion	Reproductive system and breast disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Genital rash	Reproductive system and breast disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Balanoposthitis	Reproductive system and breast disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Breast swelling	Reproductive system and breast disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Dyspareunia	Reproductive system and breast disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Genital erythema	Reproductive system and breast disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Menstruation irregular	Reproductive system and breast disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Penile haemorrhage	Reproductive system and breast disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Penile oedema	Reproductive system and breast disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Perineal fistula	Reproductive system and breast disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Pruritus genital	Reproductive system and breast disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Uterine polyp	Reproductive system and breast disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Lung disorder	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Orthopnoea	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Pleuritic pain	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Allergic sinusitis	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Apnoea	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Haemoptysis	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Hyperventilation	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Increased upper airway secretion	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Increased viscosity of bronchial secretion	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Lung consolidation	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Paranasal sinus hypersecretion	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Pleurisy	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Postnasal drip	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Respiratory disorder	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Rhonchi	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Sneezing	Respiratory, thoracic and mediastinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Purpura	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0025 affected255 at risk
Decubitus ulcer	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0024 affected255 at risk
Skin disorder	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0024 affected255 at risk
Exfoliative rash	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Yellow skin	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Hair texture abnormal	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Actinic keratosis	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Blood blister	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Dermatosis	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Hair growth abnormal	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Photosensitivity reaction	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Prurigo	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Psoriasis	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Seborrhoeic dermatitis	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Skin chapped	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Skin induration	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Toxic epidermal necrolysis	Skin and subcutaneous tissue disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Cyst drainage	Surgical and medical procedures		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Debridement	Surgical and medical procedures		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Hepatic embolisation	Surgical and medical procedures		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Mediastinal operation	Surgical and medical procedures		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Packed red blood cell transfusion	Surgical and medical procedures		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Sinus operation	Surgical and medical procedures		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Stent placement	Surgical and medical procedures		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Flushing	Vascular disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0024 affected255 at risk
Thrombophlebitis	Vascular disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk
Embolism	Vascular disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Essential hypertension	Vascular disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Jugular vein thrombosis	Vascular disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Peripheral ischaemia	Vascular disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Phlebitis	Vascular disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Cheilitis	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0023 affected255 at risk
Colitis	Gastrointestinal disorders		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0021 affected255 at risk
Blood sodium decreased	Investigations		Systematic Assessment	EG0000 affected228 at risk EG0010 affected114 at risk EG0022 affected255 at risk

ID	Title	Description
BG000	Sunitinib Double-Blind Treatment	Starting dose: 50 mg orally once daily as a single agent for 4 consecutive weeks followed by a 2-week off-treatment period to form a complete cycle of 6 weeks. (Schedule 4/2). Subjects received best supportive care in addition to the study treatment.
BG001	Placebo Double-Blind Treatment	Starting daily dose of 1 capsule, size- and color-matched to the sunitinib 50-mg capsule for 4 consecutive weeks followed by a 2-week off-treatment period to form a complete cycle of 6 weeks (Schedule 4/2). Subjects received best supportive care in addition to the study treatment. Subjects were provided the opportunity to receive open-label sunitinib at the time of confirmed disease progression or study unblinding.
BG002	Total	Total of all reporting groups

ID	Term
D009372	Neoplasms, Connective Tissue
D018204	Neoplasms, Connective and Soft Tissue
D009370	Neoplasms by Histologic Type
D009369	Neoplasms
D005770	Gastrointestinal Neoplasms
D004067	Digestive System Neoplasms
D004066	Digestive System Diseases
D005767	Gastrointestinal Diseases

ID	Term
D011758	Pyrroles
D001393	Azoles
D006573	Heterocyclic Compounds, 1-Ring
D006571	Heterocyclic Compounds
D007211	Indoles
D006574	Heterocyclic Compounds, 2-Ring
D000072471	Heterocyclic Compounds, Fused-Ring

ID	Title	Description	Serious Events (Affected)	Other Events (Affected)
EG000	Sunitinib Double-Blind Treatment	Starting dose: 50 mg orally once daily as a single agent for 4 consecutive weeks followed by a 2-week off-treatment period to form a complete cycle of 6 weeks. (Schedule 4/2). Subjects received best supportive care in addition to the study treatment.	83	223
EG001	Placebo Double-Blind Treatment	Starting daily dose of 1 capsule, size- and color-matched to the sunitinib 50-mg capsule for 4 consecutive weeks followed by a 2-week off-treatment period to form a complete cycle of 6 weeks (Schedule 4/2). Subjects received best supportive care in addition to the study treatment. Subjects were provided the opportunity to receive open-label sunitinib at the time of confirmed disease progression or study unblinding.	27	110
EG002	Sunitinib Open-Label Treatment	Subjects experiencing disease progression could have their treatment assignment unblinded, and subjects who had been receiving placebo could crossover to open-label treatment with sunitinib; subjects who had been receiving sunitinib during double-blind treatment of the study could continue to do so after unblinding if, in the opinion of the investigator, there was sufficient evidence of clinical benefit.	122	254