Comparison of Surgical Procedures to Reduce Urinary Stress Incontinence

Randomized Clinical Trial of the Burch Modified Tanagho and Autologous Fascia Sling Procedures for Women With Predominantly Stress Urinary Incontinence

The primary aim of this clinical trial is to compare the treatment success for two surgical procedures that are frequently used and have similar cure rates, yet have not been compared directly to each other in a large, rigorously conducted randomized trial. The secondary aims of the trial are to compare other outcomes for the two surgical procedures, including quality of life, sexual function, satisfaction with treatment outcomes, complications, and need for other treatment(s)after surgery. Follow-up will be a minimum of two years and up to four years.

• Predominant stress urinary incontinence by self-report,examination and test;
• Urethral hypermobility;
• Eligible for both surgical procedures;
• Ambulatory;
• Not pregnant;
• >12 months post-partum;
• No systemic disease known to affect bladder function;
• No current chemotherapy or radiation therapy;
• No urethral diverticulum, augmentation cytoplasty, or artificial sphincter;
• No recent pelvic surgery;
• Available for follow-up and able to complete study assessments;
• Signed informed consent.