Assessment of the Potential Interactions Between Cocaine and GBR 12909 - 1

Double-Blind, Placebo-Controlled, Dose Escalating, Safety and Pharmacology Study With Three Dosages of GBR 12909 in Cocaine Experienced Volunteers

The purpose of this study is to assess the potential interactions between iv cocaine and GBR 12909.

This is a single dose with escalation, double-blind, placebo-controlled inpatient study in which 24 cocaine experienced volunteers that meet protocol eligibility criteria during a 30 day screen period will be randomized into three dose groups.

Inclusion Criteria:

• Must understand study procedures and provide written informed consent
• For additional inclusion criteria information, please contact study site for more information.

Exclusion Criteria:

• Please contact study site for more information.