Study of INS365 Ophthalmic Solution in a Controlled Adverse Environment in Patients With Dry Eye

Double-Masked, Randomized, Placebo-Controlled Study of Efficacy Parameter Following Administration of INS365 Ophthalmic Solution or Placebo in a Controlled Adverse Environment (CAE) Chamber in Subjects With Non-Sjogren's Associated Dry Eye

Comparative efficacy trial of INS365 Ophthalmic Solution and placebo in patients with dry eye.

Inclusion Criteria:

• have Non-Sjogren's associated dry eye disease with symptoms lasting greater than 6 months
• had intermittent or regular artificial tear use within past 3 months

Exclusion Criteria:

• had LASIK surgery
• had punctal occlusion or cauterization within last 3 months