This study will treat patients who have a short term central catheter that is thought to be infected with a specific bacteria (gram positive bacteria)

Inclusion Criteria:

• Patients with a central indwelling catheter with signs and symptoms of infection

Exclusion Criteria:

• Patients with tunneled catheter which cannot be removed.
• Patients with evidence of endovascular infection including endocarditis.
• Patients with infection of permanent intravascular devices.
• Patients who have received more than 1 day of another antibiotic before enrollment.
• Patients with HIV and low CD4 count.