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The purpose of this study is to determine the safety and efficacy of TLK199 in patients with myelodysplastic syndrome (MDS).
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| TLK199 HCl Liposomes for Injection | Drug |
Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | United States | ||
| The Angeles Clinic & Research Institute |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 19439093 | Derived | Raza A, Galili N, Callander N, Ochoa L, Piro L, Emanuel P, Williams S, Burris H 3rd, Faderl S, Estrov Z, Curtin P, Larson RA, Keck JG, Jones M, Meng L, Brown GL. Phase 1-2a multicenter dose-escalation study of ezatiostat hydrochloride liposomes for injection (Telintra, TLK199), a novel glutathione analog prodrug in patients with myelodysplastic syndrome. J Hematol Oncol. 2009 May 13;2:20. doi: 10.1186/1756-8722-2-20. |
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| ID | Term |
|---|---|
| D009190 | Myelodysplastic Syndromes |
| ID | Term |
|---|---|
| D001855 | Bone Marrow Diseases |
| D006402 | Hematologic Diseases |
| D006425 | Hemic and Lymphatic Diseases |
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| ID | Term |
|---|---|
| D007267 | Injections |
| ID | Term |
|---|---|
| D004333 | Drug Administration Routes |
| D004358 | Drug Therapy |
| D013812 | Therapeutics |
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| Los Angeles |
| California |
| 90404 |
| United States |
| University of Chicago | Chicago | Illinois | 60637 | United States |
| Midwest Cancer Research Group | Skokie | Illinois | 60077 | United States |
| Oregon Health & Science University | Portland | Oregon | 97239 | United States |
| The Sarah Cannon Cancer Center | Nashville | Tennessee | 37203 | United States |
| Texas Cancer Associates | Dallas | Texas | 75231 | United States |
| M.D. Anderson Cancer Center | Houston | Texas | 77030 | United States |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78229 | United States |