Not provided
Not provided
| ID | Type | Description | Link |
|---|---|---|---|
| CDR0000065157 |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| National Cancer Institute (NCI) | NIH |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
RATIONALE: Radiation therapy may kill any tumor cells remaining after surgery.
PURPOSE: Phase I/II trial to study the effectiveness of brachytherapy in treating women who have stage I or stage II breast cancer.
OBJECTIVES: I. Evaluate the technical feasibility and reproducibility, cosmetic results, complication rates, and local cancer control rate experience with brachytherapy used as the sole method of radiotherapy in women with stage I/II breast cancer treated with tylectomy who have histologically assessed negative surgical margins, less than 4 positive axillary nodes, and no extracapsular nodal extension or extensive intraductal component. II. Reduce the total treatment time of breast irradiation from 6 weeks to 4-5 days in these patients.
OUTLINE: Treatment begins no sooner than 4 days and within 6 weeks after definitive surgery. All patients receive brachytherapy to the target volume (as defined by the excision cavity demarcated by post-tylectomy surgical clips plus 2 cm margin) using iridium-192 implants for dose distribution to five planes. Patients may be treated with either high-dose-rate or low-dose-rate brachytherapy at the institution's discretion. Patients are followed at 2 and 6 weeks after treatment, then at 3, 6, 9 and 12 months, then every 4 months for 1 year, every 6 months for 3 years, and then annually thereafter.
PROJECTED ACCRUAL: A maximum of 46 patients will be accrued in each group (high-dose rate vs low-dose rate) over 2 years.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| brachytherapy | Radiation |
DISEASE CHARACTERISTICS: Histologically confirmed nonlobular invasive breast cancer of one of the following histologies: Ductal Papillary Medullary Colloid (mucinous) Tubular Stage I/II (T1-2 N0-1 M0) tumor no greater than 3 cm Prior tylectomy and axillary lymph node dissection required No more than 3 positive axillary lymph nodes and no extracapsular extension At least 6 lymph nodes sampled OR Negative sentinal node Surgical clips in place delineating margins of tylectomy cavity Negative, or close but negative, inked histologic margins of tylectomy or re-excision specimen Negative margins defined as no tumor at least 2 mm away from the inked margins Close but negative margins defined as tumor within 2 mm of inked margin Positive margins defined as invasive or noninvasive tumor at inked resection margins Negative post-tylectomy or post-reexcision mammogram required if disease presented with malignancy-associated microcalcifications No remaining suspicious microcalcifications If catheters are placed at time of reexcision, the crieria may not be feasible but a post brachytherapy mammogram should be obtained as soon as possible No extensive intraductal carcinoma by the Harvard definition, i.e.: More than 25% of tumor is ductal carcinoma in situ (DCIS) and there is DCIS in adjacent breast tissue OR Intraductal carcinoma with microinvasion No proven multicentric carcinoma, i.e.: Tumor in different quadrants of the breast OR Tumor separated by at least 4 cm The following exclude: Skin or chest wall invasion Matted or fixed axillary adenopathy Metastatic internal mammary or supraclavicular nodes Paget's disease of the nipple Previously treated contralateral breast carcinoma or synchronous bilateral breast carcinoma Hormone receptor status: Not specified
PATIENT CHARACTERISTICS: Age: Any age Sex: Female Menopausal status: Not specified Performance status: Not specified Hematopoietic: Not specified Hepatic: Not specified Renal: Not specified Other: No collagen vascular disease with a c-reactive protein level above normal or with an active skin rash (e.g., systemic lupus erythematosus, scleroderma, or dermatomyositis) No coexisting medical condition that reduces life expectancy to less than 2 years No second malignancy within 5 years except nonmelanomatous skin cancer Not pregnant or nursing Negative pregnancy test
PRIOR CONCURRENT THERAPY: Biologic therapy: Not specified Chemotherapy: No prior chemotherapy for breast cancer Planned chemotherapy may begin at least 2 weeks after removal of brachytherapy catheters Endocrine therapy: Concurrent tamoxifen permitted Radiotherapy: No prior radiotherapy for breast cancer Surgery: See Disease Characteristics
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Robert R. Kuske, MD | Ochsner Cancer Institute at Ochsner Clinic Foundation | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Veterans Affairs Medical Center - Birmingham | Birmingham | Alabama | 35233 | United States | ||
| University of Alabama Comprehensive Cancer Center |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 18294778 | Result | Arthur DW, Winter K, Kuske RR, Bolton J, Rabinovitch R, White J, Hanson WF, Wilenzick RM, McCormick B. A Phase II trial of brachytherapy alone after lumpectomy for select breast cancer: tumor control and survival outcomes of RTOG 95-17. Int J Radiat Oncol Biol Phys. 2008 Oct 1;72(2):467-73. doi: 10.1016/j.ijrobp.2007.12.056. Epub 2008 Mar 4. | |
| 18035213 |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Birmingham |
| Alabama |
| 35294 |
| United States |
| Huntsville Hospital System | Huntsville | Alabama | 35801 | United States |
| Urology Associates - Mobile AL | Mobile | Alabama | 36640 | United States |
| MBCCOP - University of South Alabama | Mobile | Alabama | 36688 | United States |
| Alabama Oncology, LLC | Montgomery | Alabama | 36106-2801 | United States |
| Radiation Oncology Associates of West Alabama | Tuscallosa | Alabama | 35401 | United States |
| Providence Cancer Therapy Center | Anchorage | Alaska | 99508 | United States |
| Arizona Cancer Center | Tucson | Arizona | 85724 | United States |
| Providence Saint Joseph Medical Center - Burbank | Burbank | California | 91505 | United States |
| Mount Diablo Medical Center | Concord | California | 94524-4110 | United States |
| Beckman Research Institute, City of Hope | Duarte | California | 91010 | United States |
| California Cancer Center | Fresno | California | 93720 | United States |
| Saint Agnes Cancer Center | Fresno | California | 93720 | United States |
| Glendale Memorial Hospital and Health Center | Glendale | California | 91204 | United States |
| Sutter Health Western Division Cancer Research Group | Greenbrae | California | 94904 | United States |
| Loma Linda University Medical Center | Loma Linda | California | 92354 | United States |
| Veterans Affairs Medical Center - Long Beach | Long Beach | California | 90822 | United States |
| Kaiser Permanente Medical Center - Los Angeles | Los Angeles | California | 90027 | United States |
| USC/Norris Comprehensive Cancer Center | Los Angeles | California | 90033-0800 | United States |
| Jonsson Comprehensive Cancer Center, UCLA | Los Angeles | California | 90095-1781 | United States |
| Veterans Affairs Outpatient Clinic - Martinez | Martinez | California | 94553 | United States |
| CCOP - Bay Area Tumor Institute | Oakland | California | 94609-3305 | United States |
| Cancer Care Center | Pomona | California | 91767 | United States |
| Mercy Medical Center - Redding | Redding | California | 96099-6009 | United States |
| Radiation Oncology Center - Sacramento | Sacramento | California | 95816 | United States |
| UCSF Cancer Center and Cancer Research Institute | San Francisco | California | 94115-0128 | United States |
| Santa Cruz Radiation Oncology Medical Group, Inc. | Santa Cruz | California | 95065 | United States |
| CCOP - Santa Rosa Memorial Hospital | Santa Rosa | California | 95403 | United States |
| Stanford University | Stanford | California | 94305 | United States |
| David Grant Medical Center | Travis Air Force Base | California | 94535 | United States |
| Radiation Oncology Center - Walnut Creek | Walnut Creek | California | 94598 | United States |
| Memorial Hospital Cancer Center | Colorado Springs | Colorado | 80909 | United States |
| University of Colorado Cancer Center | Denver | Colorado | 80262 | United States |
| Bridgeport Hospital | Bridgeport | Connecticut | 06610 | United States |
| Whittingham Cancer Center | Norwalk | Connecticut | 06856 | United States |
| CCOP - Christiana Care Health Services | Wilmington | Delaware | 19899 | United States |
| Walter Reed Army Medical Center | Washington D.C. | District of Columbia | 20307-5000 | United States |
| Lykes Center for Radiation Therapy | Clearwater | Florida | 33757-0210 | United States |
| Halifax Medical Center | Daytona Beach | Florida | 32114 | United States |
| Radiation Therapy Associates - Fort Myers | Fort Myers | Florida | 33901 | United States |
| University of Florida Health Science Center | Gainesville | Florida | 32610-0296 | United States |
| Health First Holmes Regional Medical Center | Melbourne | Florida | 32901 | United States |
| Sylvester Cancer Center, University of Miami | Miami | Florida | 33136 | United States |
| Baptist Hospital of Miami | Miami | Florida | 33176-2197 | United States |
| CCOP - Mount Sinai Medical Center | Miami Beach | Florida | 33140 | United States |
| Florida Radiation Oncology Group | Orange Park | Florida | 32073 | United States |
| MD Anderson Cancer Center Orlando | Orlando | Florida | 32806 | United States |
| Gulf Coast Cancer Treatment Center | Panama City | Florida | 32405-4587 | United States |
| West Florida Cancer Institute - Pensacola | Pensacola | Florida | 32514 | United States |
| Bayfront Medical Center | St. Petersburg | Florida | 33701 | United States |
| H. Lee Moffitt Cancer Center and Research Institute | Tampa | Florida | 33612 | United States |
| Emory University Hospital - Atlanta | Atlanta | Georgia | 30322 | United States |
| CCOP - Atlanta Regional | Atlanta | Georgia | 30342-1701 | United States |
| InterCommunity Cancer Center at Rome | Rome | Georgia | 30161 | United States |
| South Georgia Medical Center | Valdosta | Georgia | 31603 | United States |
| Northwestern Memorial Hospital | Chicago | Illinois | 60611 | United States |
| University of Chicago Cancer Research Center | Chicago | Illinois | 60637 | United States |
| Ingalls Memorial Hospital | Harvey | Illinois | 60426 | United States |
| Loyola University Medical Center | Maywood | Illinois | 60153 | United States |
| Lutheran General Cancer Care Center | Park Ridge | Illinois | 60068 | United States |
| Methodist Medical Center of Illinois | Peoria | Illinois | 61636 | United States |
| CCOP - Central Illinois | Springfield | Illinois | 62526 | United States |
| CCOP - Carle Cancer Center | Urbana | Illinois | 61801 | United States |
| St. John's Medical Center | Anderson | Indiana | 46016 | United States |
| Clarion Health Partners Inc. | Indianapolis | Indiana | 46206-1367 | United States |
| Community Hospitals of Indianapolis - Regional Cancer Center | Indianapolis | Indiana | 46219 | United States |
| Ball Memorial Hospital | Muncie | Indiana | 47303-3499 | United States |
| Memorial Hospital of South Bend | South Bend | Indiana | 46601 | United States |
| St. Joseph's Radiation Oncology Center | South Bend | Indiana | 46617 | United States |
| Wendt Regional Cancer Center of Finley Hospital | Dubuque | Iowa | 52001 | United States |
| University of Iowa Hospitals and Clinics | Iowa City | Iowa | 52242 | United States |
| Medical Center at Bowling Green | Bowling Green | Kentucky | 42102 | United States |
| Veterans Affairs Medical Center - Lexington | Lexington | Kentucky | 40511-1093 | United States |
| Albert B. Chandler Medical Center, University of Kentucky | Lexington | Kentucky | 40536-0084 | United States |
| James Graham Brown Cancer Center | Louisville | Kentucky | 40202 | United States |
| Louisville Radiation Oncology | Louisville | Kentucky | 40215 | United States |
| Merle M. Mahr Cancer Center | Madisonville | Kentucky | 42431 | United States |
| Western Baptist Hospital | Paducah | Kentucky | 42001 | United States |
| Mary Bird Perkins Cancer Center | Baton Rouge | Louisiana | 70809 | United States |
| Romagosa Radiation Oncology Center | Lafayette | Louisiana | 70501 | United States |
| East Jefferson General Hospital | Metairie | Louisiana | 70011 | United States |
| MBCCOP - LSU Medical Center | New Orleans | Louisiana | 70112 | United States |
| CCOP - Ochsner | New Orleans | Louisiana | 70121 | United States |
| Maine Medical Center | Portland | Maine | 04102 | United States |
| Anne Arundel Oncology Center | Annapolis | Maryland | 21401 | United States |
| Marlene & Stewart Greenebaum Cancer Center, University of Maryland | Baltimore | Maryland | 21201 | United States |
| Greater Baltimore Medical Center and Cancer Center | Baltimore | Maryland | 21204 | United States |
| Harbor Hospital Center | Baltimore | Maryland | 21225 | United States |
| Radiation Oncology Affiliates of Maryland, P.A. | Baltimore | Maryland | 21237 | United States |
| Johns Hopkins Oncology Center | Baltimore | Maryland | 21287 | United States |
| Massachusetts General Hospital Cancer Center | Boston | Massachusetts | 02114 | United States |
| Joint Center for Radiation Therapy | Boston | Massachusetts | 02215 | United States |
| Cape Cod Hospital | Hyannis | Massachusetts | 02601 | United States |
| Veterans Affairs Medical Center - Ann Arbor | Ann Arbor | Michigan | 48105 | United States |
| CCOP - Ann Arbor Regional | Ann Arbor | Michigan | 48106 | United States |
| University of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan | 48109-0752 | United States |
| Barbara Ann Karmanos Cancer Institute | Detroit | Michigan | 48201 | United States |
| Henry Ford Hospital | Detroit | Michigan | 48202 | United States |
| Hurley Medical Center | Flint | Michigan | 48503 | United States |
| CCOP - Kalamazoo | Kalamazoo | Michigan | 49007-3731 | United States |
| Marquette General Hospital | Marquette | Michigan | 49855 | United States |
| St. Mary's Medical Center | Saginaw | Michigan | 48601 | United States |
| Mayo Clinic Cancer Center | Rochester | Minnesota | 55905 | United States |
| CCOP - Metro-Minnesota | Saint Louis Park | Minnesota | 55416 | United States |
| Ellis Fischel Cancer Center - Columbia | Columbia | Missouri | 65203 | United States |
| CCOP - Kansas City | Kansas City | Missouri | 64131 | United States |
| Cancer Research for the Ozarks | Springfield | Missouri | 65807 | United States |
| CCOP - Ozarks Regional | Springfield | Missouri | 65807 | United States |
| Veterans Affairs Medical Center - Saint Louis | St Louis | Missouri | 63106 | United States |
| St. Louis University Health Sciences Center | St Louis | Missouri | 63110-0250 | United States |
| Mallinckrodt Institute of Radiology | St Louis | Missouri | 63110 | United States |
| CCOP - Montana Cancer Consortium | Billings | Montana | 59101 | United States |
| Methodist Cancer Center - Omaha | Omaha | Nebraska | 68114 | United States |
| CCOP - Missouri Valley Cancer Consortium | Omaha | Nebraska | 68131 | United States |
| CCOP - Southern Nevada Cancer Research Foundation | Las Vegas | Nevada | 89106 | United States |
| Norris Cotton Cancer Center | Lebanon | New Hampshire | 03756 | United States |
| Elliot Regional Cancer Center | Manchester | New Hampshire | 03103 | United States |
| Veterans Affairs Medical Center - East Orange | East Orange | New Jersey | 07018-1095 | United States |
| John F. Kennedy Medical Center | Edison | New Jersey | 08818 | United States |
| Elizabeth General Medical Center - West | Elizabeth | New Jersey | 07201 | United States |
| South Jersey Hospital - Millville | Millville | New Jersey | 08332 | United States |
| Fox Chase Cancer Center at Virtua-Memorial Hospital Burlington County | Mount Holly | New Jersey | 08060 | United States |
| Community Medical Center | Toms River | New Jersey | 08755 | United States |
| St. Francis Medical Center | Trenton | New Jersey | 08629 | United States |
| Saint Joseph Medical Center | Albuquerque | New Mexico | 87102 | United States |
| Cancer Center of Albany Medical Center | Albany | New York | 12208 | United States |
| Veterans Affairs Medical Center - Albany | Albany | New York | 12208 | United States |
| State University of New York Health Science Center at Brooklyn | Brooklyn | New York | 11203 | United States |
| New York Methodist Hospital | Brooklyn | New York | 11215-3609 | United States |
| Roswell Park Cancer Institute | Buffalo | New York | 14263-0001 | United States |
| CCOP - North Shore University Hospital | Manhasset | New York | 11030 | United States |
| Kaplan Cancer Center | New York | New York | 10016 | United States |
| Memorial Sloan-Kettering Cancer Center | New York | New York | 10021 | United States |
| Champlain Valley Physicians Hospital Medical Center | Plattsburgh | New York | 12901 | United States |
| Vassar Brothers Hospital | Poughkeepsie | New York | 12601 | United States |
| Genesee Hospital - Rochester | Rochester | New York | 14607 | United States |
| University of Rochester Cancer Center | Rochester | New York | 14642 | United States |
| Albert Einstein Comprehensive Cancer Center | The Bronx | New York | 10461 | United States |
| New York Medical College | Valhalla | New York | 10595 | United States |
| Lineberger Comprehensive Cancer Center, UNC | Chapel Hill | North Carolina | 27599-7295 | United States |
| East Carolina University School of Medicine | Greenville | North Carolina | 27858-4354 | United States |
| CCOP - Southeast Cancer Control Consortium | Winston-Salem | North Carolina | 27104-4241 | United States |
| Comprehensive Cancer Center of Wake Forest University Baptist Medical Center | Winston-Salem | North Carolina | 27157-1082 | United States |
| Meritcare Roger Maris Cancer Center | Fargo | North Dakota | 58122 | United States |
| UNI-MED Medical Center | Minot | North Dakota | 58701 | United States |
| Akron General Medical Center | Akron | Ohio | 44302 | United States |
| Akron City Hospital | Akron | Ohio | 44309 | United States |
| Christ Hospital | Cincinnati | Ohio | 45219 | United States |
| Ireland Cancer Center | Cleveland | Ohio | 44106-5065 | United States |
| CCOP - Columbus | Columbus | Ohio | 43206 | United States |
| Arthur G. James Cancer Hospital - Ohio State University | Columbus | Ohio | 43210 | United States |
| Veterans Affairs Medical Center - Dayton | Dayton | Ohio | 45428 | United States |
| CCOP - Dayton | Kettering | Ohio | 45429 | United States |
| CCOP - Toledo Community Hospital Oncology Program | Toledo | Ohio | 43623-3456 | United States |
| St. John Medical Center | Tulsa | Oklahoma | 74104 | United States |
| Samaritan Regional Cancer Center | Corvallis | Oregon | 97339 | United States |
| CCOP - Columbia River Program | Portland | Oregon | 97213 | United States |
| Penn State Geisinger Medical Center | Danville | Pennsylvania | 17822-2001 | United States |
| Mercy Catholic Medical Center, Mercy Fitzgerald Divison | Darby | Pennsylvania | 19023 | United States |
| Delaware County Memorial Hospital | Drexel Hill | Pennsylvania | 19026 | United States |
| Penn State Geisinger Cancer Center | Hershey | Pennsylvania | 17033 | United States |
| Allegheny University Hospitals- Hahnemann | Philadelphia | Pennsylvania | 19102-1192 | United States |
| University of Pennsylvania Cancer Center | Philadelphia | Pennsylvania | 19104 | United States |
| Veterans Affairs Medical Center - Philadelphia | Philadelphia | Pennsylvania | 19104 | United States |
| Kimmel Cancer Center of Thomas Jefferson University - Philadelphia | Philadelphia | Pennsylvania | 19107 | United States |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | United States |
| Albert Einstein Cancer Center | Philadelphia | Pennsylvania | 19141 | United States |
| University of Pittsburgh Cancer Institute | Pittsburgh | Pennsylvania | 15213 | United States |
| Western Pennsylvania Hospital | Pittsburgh | Pennsylvania | 15224 | United States |
| Reading Hospital and Medical Center | Reading | Pennsylvania | 19612-6052 | United States |
| Mercy Hospital Cancer Center - Scranton | Scranton | Pennsylvania | 18501 | United States |
| Grand View Hospital | Sellersville | Pennsylvania | 18960 | United States |
| Wilkes Barre General Hospital | Wilkes-Barre | Pennsylvania | 18764 | United States |
| CCOP - MainLine Health | Wynnewood | Pennsylvania | 19096 | United States |
| York Hospital | York | Pennsylvania | 17315 | United States |
| Medical University of South Carolina | Charleston | South Carolina | 29425-0721 | United States |
| CCOP - Greenville | Greenville | South Carolina | 29615 | United States |
| CCOP - Upstate Carolina | Spartanburg | South Carolina | 29303 | United States |
| Jackson-Madison County General Hospital | Jackson | Tennessee | 38301 | United States |
| Baptist Regional Cancer Center - Knoxville | Knoxville | Tennessee | 37901 | United States |
| CCOP - Baptist Cancer Institute | Memphis | Tennessee | 38117 | United States |
| University of Tennessee, Memphis Cancer Center | Memphis | Tennessee | 38163 | United States |
| Vanderbilt Cancer Center | Nashville | Tennessee | 37232-6838 | United States |
| Julie and Ben Rogers Cancer Institute | Beaumont | Texas | 77701 | United States |
| University of Texas Medical Branch | Galveston | Texas | 77555-1329 | United States |
| University of Texas - MD Anderson Cancer Center | Houston | Texas | 77030 | United States |
| Wilford Hall - 59th Medical Wing | Lackland Air Force Base | Texas | 78236-5300 | United States |
| Bayshore Medical Center | Pasadena | Texas | 77504 | United States |
| LDS Hospital | Salt Lake City | Utah | 84143 | United States |
| Dixie Regional Medical Center | St. George | Utah | 84770 | United States |
| CCOP - Southwestern Vermont Regional Cancer Center | Bennington | Vermont | 05201 | United States |
| Green Mountain Oncology Group | Rutland | Vermont | 05701 | United States |
| Veterans Affairs Medical Center - White River Junction | White River Junction | Vermont | 05009 | United States |
| Martha Jefferson Hospital | Charlottesville | Virginia | 22901 | United States |
| Virginia Baptist Hospital | Lynchburg | Virginia | 24503 | United States |
| Naval Medical Center, Portsmouth | Portsmouth | Virginia | 23708-2197 | United States |
| Massey Cancer Center | Richmond | Virginia | 23298-0037 | United States |
| Swedish Hospital Tumor Institute | Seattle | Washington | 98104 | United States |
| Virginia Mason Medical Center | Seattle | Washington | 98111 | United States |
| Deaconess Medical Center | Spokane | Washington | 99210-0248 | United States |
| Yakima Valley Memorial Hospital | Yakima | Washington | 98902 | United States |
| Schiffler Oncology Center | Wheeling | West Virginia | 26003 | United States |
| St. Vincent Hospital | Green Bay | Wisconsin | 54307-3508 | United States |
| Gundersen Lutheran Medical Foundation | La Crosse | Wisconsin | 54601 | United States |
| Veterans Affairs Medical Center - Madison | Madison | Wisconsin | 53705 | United States |
| Southern Wisconsin Radiotherapy Center | Madison | Wisconsin | 53713 | United States |
| University of Wisconsin Comprehensive Cancer Center | Madison | Wisconsin | 53792 | United States |
| Marshfield Clinic | Marshfield | Wisconsin | 54449 | United States |
| Community Memorial Hospital | Menomonee Falls | Wisconsin | 53051 | United States |
| St. Joseph's Hospital | Milwaukee | Wisconsin | 53210 | United States |
| Columbia Hospital | Milwaukee | Wisconsin | 53211 | United States |
| St. Luke's Medical Center | Milwaukee | Wisconsin | 53215 | United States |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | United States |
| Veterans Affairs Medical Center - Milwaukee (Zablocki) | Milwaukee | Wisconsin | 53295 | United States |
| Southeastern Wisconsin Regional Cancer Center | Racine | Wisconsin | 53405 | United States |
| Tom Baker Cancer Center - Calgary | Calgary | Alberta | T2N 4N2 | Canada |
| Cross Cancer Institute | Edmonton | Alberta | T6G 1Z2 | Canada |
| British Columbia Cancer Agency - Vancouver Island Cancer Centre | Victoria | British Columbia | V8R 1J8 | Canada |
| Doctor Leon Richard Oncology Centre | Moncton | New Brunswick | E1C 8X3 | Canada |
| Saint John Regional Hospital | Saint John | New Brunswick | E2L 4L2 | Canada |
| Nova Scotia Cancer Centre | Halifax | Nova Scotia | B3H 1V7 | Canada |
| Northeastern Ontario Regional Cancer Centre, Sudbury | Greater Sudbury | Ontario | P3E 5J1 | Canada |
| Cancer Care Ontario-Hamilton Regional Cancer Centre | Hamilton | Ontario | L8V 5C2 | Canada |
| Kingston Regional Cancer Centre | Kingston | Ontario | K7L 5P9 | Canada |
| Cancer Care Ontario-London Regional Cancer Centre | London | Ontario | N6A 4L6 | Canada |
| Ottawa Regional Cancer Centre - Civic Campus | Ottawa | Ontario | K1Y 4K7 | Canada |
| Northwestern Ontario Regional Cancer Centre, Thunder Bay | Thunder Bay | Ontario | P7A 7T1 | Canada |
| Princess Margaret Hospital | Toronto | Ontario | M5G 2M9 | Canada |
| McGill University Department of Oncology | Montreal | Quebec | H2W 1S6 | Canada |
| Centre Hospitalier de l'Universite de Montreal | Montreal | Quebec | H2W-W1T8 | Canada |
| Saskatoon Cancer Centre | Saskatoon | Saskatchewan | S7N 4H4 | Canada |
| Ibbott GS, Hanson WF, O'Meara E, Kuske RR, Arthur D, Rabinovitch R, White J, Wilenzick RM, Harris I, Tailor RC. Dose specification and quality assurance of radiation therapy oncology group protocol 95-17; a cooperative group study of iridium-192 breast implants as sole therapy. Int J Radiat Oncol Biol Phys. 2007 Dec 1;69(5):1572-8. doi: 10.1016/j.ijrobp.2007.08.011. |
| 24041956 | Result | Rabinovitch R, Winter K, Kuske R, Bolton J, Arthur D, Scroggins T, Vicini F, McCormick B, White J. RTOG 95-17, a Phase II trial to evaluate brachytherapy as the sole method of radiation therapy for Stage I and II breast carcinoma--year-5 toxicity and cosmesis. Brachytherapy. 2014 Jan-Feb;13(1):17-22. doi: 10.1016/j.brachy.2013.08.002. Epub 2013 Sep 14. |
| Result | Kuske RR, Winter K, Arthur DW, et al.: A phase II trial of brachytherapy alone following lumpectomy for stage I or II breast cancer: initial outcomes of RTOG 9517. [Abstract] J Clin Oncol 22 (Suppl 14): A-565, 18s, 2004. |
| Result | Kuske RR, Winter K, Arthur D, et al.: A phase I/II trial of brachytherapy alone following lumpectomy for select breast cancer: toxicity analysis of Radiation Therapy Oncology Group 95-17. [Abstract] Int J Radiat Oncol Biol Phys 54(2 suppl 1): A-151, 87, 2002. |
| ID | Term |
|---|---|
| D001943 | Breast Neoplasms |
| D018270 | Carcinoma, Ductal, Breast |
| ID | Term |
|---|---|
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D001941 | Breast Diseases |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D044584 | Carcinoma, Ductal |
| D000230 | Adenocarcinoma |
| D002277 | Carcinoma |
| D009375 | Neoplasms, Glandular and Epithelial |
| D009370 | Neoplasms by Histologic Type |
| D018299 | Neoplasms, Ductal, Lobular, and Medullary |
Not provided
Not provided
| ID | Term |
|---|---|
| D001918 | Brachytherapy |
| ID | Term |
|---|---|
| D011878 | Radiotherapy |
| D013812 | Therapeutics |
Not provided
Not provided