This protocol is to provide continuing medical/surgical/radio-therapeutic care, treatment and follow-up for NCI patients not currently entered on an active research protocol. No investigational treatments will be administered on this protocol.

Background:

It may be in the interest of the CCR to continue to follow and treat certain subjects after they have completed their treatment and participation on a research protocol.

Objective:

To provide continuing treatment and medical follow-up for CCR subjects who have completed their treatment and participation on a research protocol and who are not currently entered on or eligible for another active research protocol.

Eligibility:

Subjects who have been previously enrolled on and received treatment according to an approved CCR research protocol. (clinical trial)

It is in the best interest of the subject and the CCR for the subject to continue to receive standard care and follow-up at the NIH.

Design:

Medical/surgical/radiotherapeutic care, treatment and follow-up is provided for CCR subjects who have completed their treatment and participation on a research protocol and who are not currently entered on an active research protocol.

No investigational treatments will be administered. This protocol is not be used as a platform to perform pilot studies of off-label uses for standard agents.

• INCLUSION CRITERIA:

Subjects of any age who have been previously enrolled and treated on an approved CCR research treatment protocol.

It is in the best interests of the subject and the CCR for the subject to continue to receive treatment and follow-up at the NIH.

The subject or guardian signs the informed consent and agrees to the proposed treatment regimen.

EXCLUSION CRITERIA:

Subjects who have not been previously treated on a CCR research treatment protocol.

Subjects who are receiving an investigational therapy.