Not provided
Not provided
Not provided
| ID | Type | Description | Link |
|---|---|---|---|
| 83-M-0176 |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
This study will allow researchers to use various types of tests to evaluate cognitive and sensory functions. These tests, referred to as "batteries" will evaluate attention, executive functions, general intellectual functioning, language, memory, motor functions, orientation, personality, selected sensory and perceptual functions, vigilance (alertness), and visual-spatial functions. Children and adult patient will receive different test batteries.
The goals of this research study are to;
Neuropsychological tests are used to provide an assessment of cognitive functions in patients with idiopathic generalized epileptic (IGE) disorders and their first-degree relatives. The battery comprises tests designed to tap attention, memory, selected sensory and perceptual functions, vigilance, and visual-spatial functions. Modified batteries have been developed for the assessment of children ages 5-8, and children ages 8-16. The data provided by these batteries are compared with genetic profiles of the same participants that have been ascertained from blood samples analyzed by colleagues at the Mount Sinai School of Medicine/Columbia University in New York City.
Not provided
Not provided
Not provided
Not provided
Not provided
Patients.
Normal volunteers.
EXCLUSION CRITERIA:
Subjects over 95 years of age.
Subjects with a history of alcohol or drug abuse, psychopathology, or central nervous system pathology, other than that which defines group membership, may be excluded.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Childrens National Medical Center | Washington D.C. | District of Columbia | United States | |||
| National Institutes of Health Clinical Center, 9000 Rockville Pike |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 2727213 | Background | Johnstone EC, Owens DG, Bydder GM, Colter N, Crow TJ, Frith CD. The spectrum of structural brain changes in schizophrenia: age of onset as a predictor of cognitive and clinical impairments and their cerebral correlates. Psychol Med. 1989 Feb;19(1):91-103. doi: 10.1017/s0033291700011053. |
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D001008 | Anxiety Disorders |
| D006259 | Craniocerebral Trauma |
| D019964 | Mood Disorders |
| D012559 | Schizophrenia |
| D012640 | Seizures |
| D007802 | Language |
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D001523 | Mental Disorders |
| D020196 | Trauma, Nervous System |
| D009422 | Nervous System Diseases |
| D014947 | Wounds and Injuries |
Not provided
Not provided
| Bethesda |
| Maryland |
| 20892 |
| United States |
| Henry Ford Health Systems | Detroit | Michigan | 48202 | United States |
| Mt. Sinai Medical Center | New York | New York | 10029-0574 | United States |
| Columbia University | New York | New York | 10032-3784 | United States |
| Genethon | Every Cedex | France |
| Mosco Research Institute of Psychiatry | Moscow | Russia |
| D019967 |
| Schizophrenia Spectrum and Other Psychotic Disorders |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D003142 | Communication |
| D001519 | Behavior |