Evaluation of Lofexidine for Treatment of Opiate Withdrawal
Evaluation of Lofexidine for Treatment of Opiate Withdrawal
The purpose of this study is to assess the safety of lofexidine in the treatment of opiate-dependent individuals.
Inclusion Criteria:
M/F ages 21-50. Meet DSM-IV criteria for opiate dependence. Agree to conditions of the study and sign informed consent.
Exclusion Criteria:
Psychiatric disorder that requires medication therapy. History of seizures. Pregnant and/or nuring women. Dependence on ETOH or benzodiazepines or other sedative/hypnotics. Acute hepatitis. Other medical condtions that deem participation to be unsafe.